3ZD2

THE STRUCTURE OF THE TWO N-TERMINAL DOMAINS OF COMPLEMENT FACTOR H RELATED PROTEIN 1 SHOWS FORMATION OF A NOVEL DIMERISATION INTERFACE

Summary for 3ZD2

• Entry DOI: 10.2210/pdb3zd2/pdb
• Related: 3ZD1
• Descriptor: COMPLEMENT FACTOR H-RELATED PROTEIN 1, 1,2-ETHANEDIOL (3 entities in total)
• Functional Keywords: immune system, cfhr-1, cfhr1, fhr1
• Biological source: HOMO SAPIENS (HUMAN)
• Cellular location: Secreted: Q03591
• Total number of polymer chains: 2
• Total formula weight: 29791.04

Authors

Caesar, J.J.E.,Goicoechea de Jorge, E.,Pickering, M.C.,Lea, S.M. (deposition date: 2012-11-23, release date: 2013-03-13, Last modification date: 2023-12-20)

• Primary citation: Goicoechea De Jorge, E.,Caesar, J.J.E.,Malik, T.H.,Patel, M.,Colledge, M.,Johnson, S.,Hakobyan, S.,Morgan, B.P.,Harris, C.L.,Pickering, M.C.,Lea, S.M.; Dimerization of Complement Factor H-Related Proteins Modulates Complement Activation in Vivo.; Proc.Natl.Acad.Sci.USA, 110:4685-, 2013; PubMed: 23487775; DOI: 10.1073/PNAS.1219260110

Experimental method

X-RAY DIFFRACTION (1.99 Å)