3ZD2
THE STRUCTURE OF THE TWO N-TERMINAL DOMAINS OF COMPLEMENT FACTOR H RELATED PROTEIN 1 SHOWS FORMATION OF A NOVEL DIMERISATION INTERFACE
Summary for 3ZD2
Entry DOI | 10.2210/pdb3zd2/pdb |
Related | 3ZD1 |
Descriptor | COMPLEMENT FACTOR H-RELATED PROTEIN 1, 1,2-ETHANEDIOL (3 entities in total) |
Functional Keywords | immune system, cfhr-1, cfhr1, fhr1 |
Biological source | HOMO SAPIENS (HUMAN) |
Cellular location | Secreted: Q03591 |
Total number of polymer chains | 2 |
Total formula weight | 29791.04 |
Authors | Caesar, J.J.E.,Goicoechea de Jorge, E.,Pickering, M.C.,Lea, S.M. (deposition date: 2012-11-23, release date: 2013-03-13, Last modification date: 2023-12-20) |
Primary citation | Goicoechea De Jorge, E.,Caesar, J.J.E.,Malik, T.H.,Patel, M.,Colledge, M.,Johnson, S.,Hakobyan, S.,Morgan, B.P.,Harris, C.L.,Pickering, M.C.,Lea, S.M. Dimerization of Complement Factor H-Related Proteins Modulates Complement Activation in Vivo. Proc.Natl.Acad.Sci.USA, 110:4685-, 2013 Cited by PubMed: 23487775DOI: 10.1073/PNAS.1219260110 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.99 Å) |
Structure validation
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