3ZD2

THE STRUCTURE OF THE TWO N-TERMINAL DOMAINS OF COMPLEMENT FACTOR H RELATED PROTEIN 1 SHOWS FORMATION OF A NOVEL DIMERISATION INTERFACE

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 1126

Chain	Residue
A	LEU15
A	ASP17
B	EDO1125

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1127

Chain	Residue
A	TYR16
A	PHE33
A	TYR34
B	PRO72

---

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO B 1124

Chain	Residue
A	LEU68
B	PHE48

---

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO A 1128

Chain	Residue
A	GLU1
A	VAL74
A	GLU75
A	ASN76
A	GLY77
A	HIS78
A	ASN97
B	THR98

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1129

Chain	Residue
A	THR3
A	GLN26
A	PRO28
A	SER45

---

site_id	AC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO B 1125

Chain	Residue
A	TRP49
A	EDO1126
B	TYR39
B	ASN40
B	EDO1128

---

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 1130

Chain	Residue
A	GLY83
A	THR85
B	TRP49

---

site_id	AC8
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO B 1126

Chain	Residue
B	SER36
B	CYS37
B	VAL42
B	SER43
B	LYS46
B	SER47
B	PHE48
B	HOH2012

---

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE EDO B 1127

Chain	Residue
B	THR50
B	ARG51

---

site_id	BC1
Number of Residues	8
Details	BINDING SITE FOR RESIDUE EDO B 1128

Chain	Residue
A	PHE48
A	TRP49
B	ASN40
B	LEU68
B	CYS69
B	PHE70
B	TRP116
B	EDO1125

---

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO B 1129

Chain	Residue
A	PRO72
A	PHE73
B	TYR16
B	TYR21
B	VAL32

---

site_id	BC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 1131

Chain	Residue
A	VAL74
A	GLU75
A	LYS121
A	CYS122
A	HOH2043

---

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE EDO A 1132

Chain	Residue
A	SER36
A	CYS37
A	PHE48
A	HOH2028
A	HOH2074

---

site_id	BC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE EDO A 1133

Chain	Residue
A	ARG114
A	TRP116
A	SER117

---

site_id	BC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE EDO A 1134

Chain	Residue
A	GLN84
A	THR85
A	ASP90
B	GLU57

---

site_id	BC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE EDO B 1130

Chain	Residue
A	THR91
A	ASN108
A	SER110
B	GLU88
B	VAL112
B	GLU113

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	62
Details	Domain: {"description":"Sushi 1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00302","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	57
Details	Domain: {"description":"Sushi 2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00302","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"16335952","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---