5DQ8
Crystal structure of human transcription factor TEAD2 in complex with flufenamic acid
Summary for 5DQ8
Entry DOI | 10.2210/pdb5dq8/pdb |
Related | 3L15 5DQE |
Descriptor | Transcriptional enhancer factor TEF-4, 2-[[3-(TRIFLUOROMETHYL)PHENYL]AMINO] BENZOIC ACID (3 entities in total) |
Functional Keywords | flufenamates, cancer therapy, hippo pathway, transcription |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 2 |
Total formula weight | 55821.88 |
Authors | |
Primary citation | Pobbati, A.V.,Han, X.,Hung, A.W.,Weiguang, S.,Huda, N.,Chen, G.Y.,Kang, C.,Chia, C.S.,Luo, X.,Hong, W.,Poulsen, A. Targeting the Central Pocket in Human Transcription Factor TEAD as a Potential Cancer Therapeutic Strategy. Structure, 23:2076-2086, 2015 Cited by PubMed: 26592798DOI: 10.1016/j.str.2015.09.009 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.305 Å) |
Structure validation
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