PDB: 406 resultsInfo pagesStatus searchChemie searchBIRD

---

5J7C	A picomolar affinity FN3 domain in complex with hen egg-white lysozyme Descriptor: FNfn10-anti-lysozyme (DE0.4.1), Lysozyme C Authors: Porebski, B.T, Drinkwater, N, McGowan, S, Buckle, A.M. Deposit date: 2016-04-06 Release date: 2016-08-17 Last modified: 2023-09-27 Method: X-RAY DIFFRACTION (2.535 Å) Cite: Circumventing the stability-function trade-off in an engineered FN3 domain. Protein Eng.Des.Sel., 2016
7OPB	IL7R in complex with an antagonist Descriptor: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, IL7R binder, ... Authors: Markovic, I, Verschueren, K.H.G, Verstraete, K, Savvides, S.N. Deposit date: 2021-05-31 Release date: 2022-05-11 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.144 Å) Cite: Design of protein-binding proteins from the target structure alone. Nature, 605, 2022
6ZZ8	MB_CRS6-15 bound to CrSAS-6_6HR Descriptor: Centriole protein, Protein B Authors: Hatzopoulos, G.N, Kukenshoner, T, Banterle, N, Favez, T, Fluckiger, I, Hantschel, O, Gonczy, P. Deposit date: 2020-08-04 Release date: 2021-07-07 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (3.73 Å) Cite: Tuning SAS-6 architecture with monobodies impairs distinct steps of centriole assembly. Nat Commun, 12, 2021
7BWA	Cryo-EM Structure for the Ectodomain of the Full-length Human Insulin Receptor in Complex with 2 Insulin Descriptor: Insulin fusion, Insulin receptor Authors: Yu, D, Zhang, X, Sun, J, Li, X, Wu, Z, Han, X, Fan, C, Ma, Y, Ouyang, Q, Wang, T. Deposit date: 2020-04-14 Release date: 2021-04-14 Method: ELECTRON MICROSCOPY (4.9 Å) Cite: Insulin Binding Induced the Ectodomain Conformational Dynamics in the Full-length Human Insulin Receptor To Be Published
7PG2	Low resolution Cryo-EM structure of full-length insulin receptor bound to 3 insulin, conf 1 Descriptor: Insulin, Isoform Short of Insulin receptor Authors: Nielsen, J.A, Slaaby, R, Boesen, T, Hummelshoj, T, Brandt, J, Schluckebier, G, Nissen, P. Deposit date: 2021-08-12 Release date: 2022-02-02 Last modified: 2022-02-16 Method: ELECTRON MICROSCOPY (6.7 Å) Cite: Structural Investigations of Full-Length Insulin Receptor Dynamics and Signalling. J.Mol.Biol., 434, 2022
7PG0	Low resolution Cryo-EM structure of full-length insulin receptor bound to 3 insulin with visible ddm micelle, conf 1 Descriptor: Insulin, Isoform Short of Insulin receptor Authors: Nielsen, J.A, Slaaby, R, Boesen, T, Hummelshoj, T, Brandt, J, Schluckebier, G, Nissen, P. Deposit date: 2021-08-12 Release date: 2022-02-02 Last modified: 2022-02-16 Method: ELECTRON MICROSCOPY (7.6 Å) Cite: Structural Investigations of Full-Length Insulin Receptor Dynamics and Signalling. J.Mol.Biol., 434, 2022
7PG4	Low resolution Cryo-EM structure of the full-length insulin receptor bound to 2 insulin, conf 3 Descriptor: Insulin, Isoform Short of Insulin receptor Authors: Nielsen, J.A, Slaaby, R, Boesen, T, Hummelshoj, T, Brandt, J, Schluckebier, G, Nissen, P. Deposit date: 2021-08-12 Release date: 2022-02-02 Last modified: 2022-02-16 Method: ELECTRON MICROSCOPY (9.1 Å) Cite: Structural Investigations of Full-Length Insulin Receptor Dynamics and Signalling. J.Mol.Biol., 434, 2022
7PG3	Low resolution Cryo-EM structure of the full-length insulin receptor bound to 3 insulin, conf 2 Descriptor: Insulin, Isoform Short of Insulin receptor Authors: Nielsen, J.A, Slaaby, R, Boesen, T, Hummelshoj, T, Brandt, J, Schluckebier, G, Nissen, P. Deposit date: 2021-08-12 Release date: 2022-02-02 Last modified: 2022-02-16 Method: ELECTRON MICROSCOPY (7.3 Å) Cite: Structural Investigations of Full-Length Insulin Receptor Dynamics and Signalling. J.Mol.Biol., 434, 2022
5FMV	Crystal structure of human CD45 extracellular region, domains d1-d4 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C, SULFATE ION Authors: Chang, V.T, Fernandes, R.A, Ganzinger, K.A, Lee, S.F, Siebold, C, McColl, J, Jonsson, P, Palayret, M, Harlos, K, Coles, C.H, Jones, E.Y, Lui, Y, Huang, E, Gilbert, R.J.C, Klenerman, D, Aricescu, A.R, Davis, S.J. Deposit date: 2015-11-09 Release date: 2016-03-23 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Initiation of T Cell Signaling by Cd45 Segregation at 'Close Contacts'. Nat.Immunol., 17, 2016
8QY4	Structure of interleukin 11 (gp130 P496L mutant). Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-11, ... Authors: Gardner, S, Bubeck, D, Jin, Y. Deposit date: 2023-10-25 Release date: 2024-02-21 Last modified: 2024-09-04 Method: ELECTRON MICROSCOPY (3.06 Å) Cite: Structural insights into IL-11-mediated signalling and human IL6ST variant-associated immunodeficiency. Nat Commun, 15, 2024
8QY5	Structure of interleukin 6. Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6, ... Authors: Gardner, S, Bubeck, D, Jin, Y. Deposit date: 2023-10-25 Release date: 2024-02-21 Last modified: 2024-09-04 Method: ELECTRON MICROSCOPY (3.1 Å) Cite: Structural insights into IL-11-mediated signalling and human IL6ST variant-associated immunodeficiency. Nat Commun, 15, 2024
8QY6	Structure of interleukin 6 (gp130 P496L mutant). Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-6, ... Authors: Gardner, S, Bubeck, D, Jin, Y. Deposit date: 2023-10-25 Release date: 2024-02-21 Last modified: 2024-09-04 Method: ELECTRON MICROSCOPY (3.16 Å) Cite: Structural insights into IL-11-mediated signalling and human IL6ST variant-associated immunodeficiency. Nat Commun, 15, 2024
5J11	Structure of human TSLP in complex with TSLPR and IL-7Ralpha Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Cytokine receptor-like factor 2, Interleukin-7 receptor subunit alpha, ... Authors: Verstraete, K, Savvides, S.N. Deposit date: 2016-03-28 Release date: 2017-04-05 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (2.56 Å) Cite: Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma. Nat Commun, 8, 2017
5FM5	Crystal structure of the myomesin:obscurin-like-1 complex Descriptor: MYOMESIN-1, OBSCURIN-LIKE-1 Authors: Pernigo, S, Steiner, R.A. Deposit date: 2015-11-01 Release date: 2016-11-23 Last modified: 2024-01-10 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Binding of Myomesin to Obscurin-Like-1 at the Muscle M-Band Provides a Strategy for Isoform-Specific Mechanical Protection. Structure, 25, 2017
8Q6T	Helical reconstruction of the relaxed thick filament from FIB milled left ventricular mouse myofibrils Descriptor: Myosin binding protein C, cardiac, Myosin light chain 3, ... Authors: Tamborrini, D, Raunser, S. Deposit date: 2023-08-14 Release date: 2023-11-01 Last modified: 2023-12-06 Method: ELECTRON MICROSCOPY (18 Å) Cite: Structure of the native myosin filament in the relaxed cardiac sarcomere. Nature, 623, 2023
7BW7	Cryo-EM Structure for the Ectodomain of the Full-length Human Insulin Receptor in Complex with 1 Insulin. Descriptor: Insulin fusion, Insulin receptor Authors: Yu, D, Zhang, X, Sun, J, Li, X, Wu, Z, Han, X, Fan, C, Ma, Y, Ouyang, Q, Wang, T. Deposit date: 2020-04-13 Release date: 2021-04-14 Method: ELECTRON MICROSCOPY (4.1 Å) Cite: Insulin Binding Induced the Ectodomain Conformational Dynamics in the Full-length Human Insulin Receptor To Be Published
7BW8	Cryo-EM Structure for the Insulin Binding Region in the Ectodomain of the Full-length Human Insulin Receptor in Complex with 1 Insulin Descriptor: Insulin fusion, Insulin receptor Authors: Yu, D, Zhang, X, Sun, J, Li, X, Wu, Z, Han, X, Fan, C, Ma, Y, Ouyang, Q, Wang, T. Deposit date: 2020-04-14 Release date: 2021-04-14 Method: ELECTRON MICROSCOPY (3.8 Å) Cite: Insulin Binding Induced the Ectodomain Conformational Dynamics in the Full-length Human Insulin Receptor To Be Published
7CEG	Crystal structure of the complex between mouse PTP delta and neuroligin-3 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Isoform C of Receptor-type tyrosine-protein phosphatase delta, Neuroligin-3 Authors: Yamagata, A, Yoshida, T, Shiroshima, T, Maeda, A, Fukai, S. Deposit date: 2020-06-23 Release date: 2021-02-24 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (3.85 Å) Cite: Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice. Nat Commun, 12, 2021
7F7Q	Enterococcus faecalis GH31 alpha-N-acetylgalactosaminidase D455A in complex with p-nitrophenyl alpha-N-acetylgalactosaminide Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-galactopyranose, GH31 alpha-N-acetylgalactosaminidase, ... Authors: Miyazaki, T. Deposit date: 2021-06-30 Release date: 2021-12-08 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.42 Å) Cite: Structural and mechanistic insights into the substrate specificity and hydrolysis of GH31 alpha-N-acetylgalactosaminidase. Biochimie, 195, 2022
7F7R	Enterococcus faecalis GH31 alpha-N-acetylgalactosaminidase D455N in complex with Tn antigen Descriptor: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-alpha-D-galactopyranose, CALCIUM ION, ... Authors: Miyazaki, T. Deposit date: 2021-06-30 Release date: 2021-12-08 Last modified: 2023-11-29 Method: X-RAY DIFFRACTION (1.63 Å) Cite: Structural and mechanistic insights into the substrate specificity and hydrolysis of GH31 alpha-N-acetylgalactosaminidase. Biochimie, 195, 2022
6IAA	hRobo2 ectodomain Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Roundabout homolog 2, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose Authors: Barak, R, Isupov, N.M, Opatowsky, Y. Deposit date: 2018-11-26 Release date: 2019-03-13 Last modified: 2020-07-29 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Structural Principles in Robo Activation and Auto-inhibition. Cell, 177, 2019
6HN4	Leucine-zippered human insulin receptor ectodomain with single bound insulin - "lower" membrane-proximal part Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin receptor,Insulin receptor,General control protein GCN4 Authors: Weis, F, Menting, J.G, Margetts, M.B, Chan, S.J, Xu, Y, Tennagels, N, Wohlfart, P, Langer, T, Mueller, C.W, Dreyer, M.K, Lawrence, M.C. Deposit date: 2018-09-14 Release date: 2018-11-21 Last modified: 2022-03-30 Method: ELECTRON MICROSCOPY (4.2 Å) Cite: The signalling conformation of the insulin receptor ectodomain. Nat Commun, 9, 2018
6YGN	Titin kinase and its flanking domains Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Titin Authors: Fleming, J.R, Franke, B, Bogomolovas, J, Mayans, O. Deposit date: 2020-03-27 Release date: 2021-04-07 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Titin kinase ubiquitination aligns autophagy receptors with mechanical signals in the sarcomere. Embo Rep., 22, 2021
6HN5	Leucine-zippered human insulin receptor ectodomain with single bound insulin - "upper" membrane-distal part Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Insulin, ... Authors: Weis, F, Menting, J.G, Margetts, M.B, Chan, S.J, Xu, Y, Tennagels, N, Wohlfart, P, Langer, T, Mueller, C.W, Dreyer, M.K, Lawrence, M.C. Deposit date: 2018-09-14 Release date: 2018-11-21 Last modified: 2022-03-30 Method: ELECTRON MICROSCOPY (3.2 Å) Cite: The signalling conformation of the insulin receptor ectodomain. Nat Commun, 9, 2018
1A22	HUMAN GROWTH HORMONE BOUND TO SINGLE RECEPTOR Descriptor: GROWTH HORMONE, GROWTH HORMONE RECEPTOR Authors: De Vos, A.M, Ultsch, M. Deposit date: 1998-01-15 Release date: 1998-04-29 Last modified: 2023-08-02 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Structural and functional analysis of the 1:1 growth hormone:receptor complex reveals the molecular basis for receptor affinity. J.Mol.Biol., 277, 1998

<34567891011121314151617>