5J7C

A picomolar affinity FN3 domain in complex with hen egg-white lysozyme

Summary for 5J7C

• Entry DOI: 10.2210/pdb5j7c/pdb
• Related: 5J7K
• Descriptor: Lysozyme C, FNfn10-anti-lysozyme (DE0.4.1) (3 entities in total)
• Functional Keywords: yeast surface display, high affinity, fibronectin type iii, fn3, protein binding-hydrolase complex, protein binding/hydrolase
• Biological source: Homo sapiens; More
• Cellular location: Secreted: P00698
• Total number of polymer chains: 4
• Total formula weight: 51255.64

Authors

Porebski, B.T.,Drinkwater, N.,McGowan, S.,Buckle, A.M. (deposition date: 2016-04-06, release date: 2016-08-17, Last modification date: 2023-09-27)

• Primary citation: Porebski, B.T.,Conroy, P.J.,Drinkwater, N.,Schofield, P.,Vazquez-Lombardi, R.,Hunter, M.R.,Hoke, D.E.,Christ, D.,McGowan, S.,Buckle, A.M.; Circumventing the stability-function trade-off in an engineered FN3 domain.; Protein Eng.Des.Sel., 2016; PubMed: 27578887; DOI: 10.1093/protein/gzw046

Experimental method

X-RAY DIFFRACTION (2.535 Å)