5J7K
Loop grafting onto a highly stable FN3 scaffold
Summary for 5J7K
Entry DOI | 10.2210/pdb5j7k/pdb |
Related | 5J7C |
Descriptor | FN3con-a-lys, ZINC ION (3 entities in total) |
Functional Keywords | loop grafting, rational design, fibronectin type iii, fn3, protein binding, protein binding-hydrolase complex |
Biological source | synthetic construct |
Total number of polymer chains | 8 |
Total formula weight | 89075.76 |
Authors | Porebski, B.T.,Drinkwater, N.,McGowan, S.,Buckle, A.M. (deposition date: 2016-04-06, release date: 2016-08-17, Last modification date: 2023-09-27) |
Primary citation | Porebski, B.T.,Conroy, P.J.,Drinkwater, N.,Schofield, P.,Vazquez-Lombardi, R.,Hunter, M.R.,Hoke, D.E.,Christ, D.,McGowan, S.,Buckle, A.M. Circumventing the stability-function trade-off in an engineered FN3 domain. Protein Eng.Des.Sel., 2016 Cited by PubMed: 27578887DOI: 10.1093/protein/gzw046 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.46 Å) |
Structure validation
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