5FMV

Crystal structure of human CD45 extracellular region, domains d1-d4

Summary for 5FMV

• Entry DOI: 10.2210/pdb5fmv/pdb
• Related: 5FN6 5FN7 5FN8
• Descriptor: RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C, 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION (3 entities in total)
• Functional Keywords: hydrolase, receptor protein tyrosine phosphatase, cd45, ptprc
• Biological source: HOMO SAPIENS (HUMAN)
• Total number of polymer chains: 2
• Total formula weight: 86214.94

Authors

Chang, V.T.,Fernandes, R.A.,Ganzinger, K.A.,Lee, S.F.,Siebold, C.,McColl, J.,Jonsson, P.,Palayret, M.,Harlos, K.,Coles, C.H.,Jones, E.Y.,Lui, Y.,Huang, E.,Gilbert, R.J.C.,Klenerman, D.,Aricescu, A.R.,Davis, S.J. (deposition date: 2015-11-09, release date: 2016-03-23, Last modification date: 2020-07-29)

• Primary citation: Chang, V.T.,Fernandes, R.A.,Ganzinger, K.A.,Lee, S.F.,Siebold, C.,Mccoll, J.,Jonsson, P.,Palayret, M.,Harlos, K.,Coles, C.H.,Jones, E.Y.,Lui, Y.,Huang, E.,Gilbert, R.J.,Klenerman, D.,Aricescu, A.R.,Davis, S.J.; Initiation of T Cell Signaling by Cd45 Segregation at 'Close Contacts'.; Nat.Immunol., 17:574-, 2016; PubMed: 26998761; DOI: 10.1038/NI.3392

Experimental method

X-RAY DIFFRACTION (2.9 Å)