Crystal structure of human CD45 extracellular region, domains d1-d4

Summary for 5FMV

Related5FN6 5FN7 5FN8
DescriptorRECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE C, 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION (3 entities in total)
Functional Keywordshydrolase, receptor protein tyrosine phosphatase, cd45, ptprc
Biological sourceHOMO SAPIENS (HUMAN)
Total number of polymer chains2
Total molecular weight86214.94
Primary citation
Chang, V.T.,Fernandes, R.A.,Ganzinger, K.A.,Lee, S.F.,Siebold, C.,Mccoll, J.,Jonsson, P.,Palayret, M.,Harlos, K.,Coles, C.H.,Jones, E.Y.,Lui, Y.,Huang, E.,Gilbert, R.J.,Klenerman, D.,Aricescu, A.R.,Davis, S.J.
Initiation of T Cell Signaling by Cd45 Segregation at 'Close Contacts'.
Nat.Immunol., 17:574-, 2016
PubMed: 26998761 (PDB entries with the same primary citation)
DOI: 10.1038/NI.3392
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.2803 1.2% 6.2% 9.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-11-25