7CEG

Crystal structure of the complex between mouse PTP delta and neuroligin-3

Summary for 7CEG

Entry DOI	10.2210/pdb7ceg/pdb
Descriptor	Isoform C of Receptor-type tyrosine-protein phosphatase delta, Neuroligin-3, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	synapse organization, trans-synaptic complex, esterase domain, hydrolase-cell adhesion complex, hydrolase/cell adhesion
Biological source	Mus musculus (Mouse) More
Total number of polymer chains	2
Total formula weight	107777.83
Authors	Yamagata, A.,Yoshida, T.,Shiroshima, T.,Maeda, A.,Fukai, S. (deposition date: 2020-06-23, release date: 2021-02-24, Last modification date: 2023-11-29)
Primary citation	Yoshida, T.,Yamagata, A.,Imai, A.,Kim, J.,Izumi, H.,Nakashima, S.,Shiroshima, T.,Maeda, A.,Iwasawa-Okamoto, S.,Azechi, K.,Osaka, F.,Saitoh, T.,Maenaka, K.,Shimada, T.,Fukata, Y.,Fukata, M.,Matsumoto, J.,Nishijo, H.,Takao, K.,Tanaka, S.,Okabe, S.,Tabuchi, K.,Uemura, T.,Mishina, M.,Mori, H.,Fukai, S. Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice. Nat Commun, 12:1848-1848, 2021 Cited by PubMed: 33758193 DOI: 10.1038/s41467-021-22059-6 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.85 Å)

Structure validation