7PG0

Low resolution Cryo-EM structure of full-length insulin receptor bound to 3 insulin with visible ddm micelle, conf 1

Summary for 7PG0

• Entry DOI: 10.2210/pdb7pg0/pdb
• EMDB information: 13385
• Descriptor: Isoform Short of Insulin receptor, Insulin (3 entities in total)
• Functional Keywords: insulin, receptor, complex, membrane protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 8
• Total formula weight: 330848.11

Authors

Nielsen, J.A.,Slaaby, R.,Boesen, T.,Hummelshoj, T.,Brandt, J.,Schluckebier, G.,Nissen, P. (deposition date: 2021-08-12, release date: 2022-02-02, Last modification date: 2022-02-16)

• Primary citation: Nielsen, J.,Brandt, J.,Boesen, T.,Hummelshoj, T.,Slaaby, R.,Schluckebier, G.,Nissen, P.; Structural Investigations of Full-Length Insulin Receptor Dynamics and Signalling.; J.Mol.Biol., 434:167458-167458, 2022; PubMed: 35074483; DOI: 10.1016/j.jmb.2022.167458

Experimental method

ELECTRON MICROSCOPY (7.6 Å)