7OPB
IL7R in complex with an antagonist
Summary for 7OPB
Entry DOI | 10.2210/pdb7opb/pdb |
Descriptor | Interleukin-7 receptor subunit alpha, IL7R binder, TRIETHYLENE GLYCOL, ... (6 entities in total) |
Functional Keywords | protein binder, il7r, antagonist, protein binding |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 88465.52 |
Authors | Markovic, I.,Verschueren, K.H.G.,Verstraete, K.,Savvides, S.N. (deposition date: 2021-05-31, release date: 2022-05-11, Last modification date: 2024-01-31) |
Primary citation | Cao, L.,Coventry, B.,Goreshnik, I.,Huang, B.,Sheffler, W.,Park, J.S.,Jude, K.M.,Markovic, I.,Kadam, R.U.,Verschueren, K.H.G.,Verstraete, K.,Walsh, S.T.R.,Bennett, N.,Phal, A.,Yang, A.,Kozodoy, L.,DeWitt, M.,Picton, L.,Miller, L.,Strauch, E.M.,DeBouver, N.D.,Pires, A.,Bera, A.K.,Halabiya, S.,Hammerson, B.,Yang, W.,Bernard, S.,Stewart, L.,Wilson, I.A.,Ruohola-Baker, H.,Schlessinger, J.,Lee, S.,Savvides, S.N.,Garcia, K.C.,Baker, D. Design of protein-binding proteins from the target structure alone. Nature, 605:551-560, 2022 Cited by PubMed: 35332283DOI: 10.1038/s41586-022-04654-9 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.144 Å) |
Structure validation
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