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7OPB

IL7R in complex with an antagonist

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B, C
(A, B, C)
Interleukin-7 receptor subunit alphapolymer19622862.23UniProt (P16871)
Pfam (PF18447)
Pfam (PF00041)
Homo sapiens (Human)IL-7 receptor subunit alpha,IL-7R subunit alpha,IL-7R-alpha,IL-7RA,CDw127
2D, E, F
(D, E, F)
IL7R binderpolymer556443.43Escherichia coli BL21(DE3)
3G
(A)
TRIETHYLENE GLYCOLnon-polymer150.21Chemie (PGE)
4H, J, L
(A, C, E)
1,2-ETHANEDIOLnon-polymer62.13Chemie (EDO)
5I, K
(B, C)
DI(HYDROXYETHYL)ETHERnon-polymer106.12Chemie (PEG)
6M, N, O, P, Q...
(A, B, C, D, E...)
waterwater18.0309Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains6
Total formula weight87916.9
Non-Polymers*Number of molecules6
Total formula weight548.6
All*Total formula weight88465.5
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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