8Q6T

Helical reconstruction of the relaxed thick filament from FIB milled left ventricular mouse myofibrils

This is a non-PDB format compatible entry.

Summary for 8Q6T

• Entry DOI: 10.2210/pdb8q6t/pdb
• EMDB information: 18198
• Descriptor: Myosin-7, Myosin light chain 3, Myosin regulatory light chain 2, ventricular/cardiac muscle isoform, ... (5 entities in total)
• Functional Keywords: mammalian, muscle, thick filament, cardiac, motor protein
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 22
• Total formula weight: 1879464.47

Authors

Tamborrini, D.,Raunser, S. (deposition date: 2023-08-14, release date: 2023-11-01, Last modification date: 2023-12-06)

• Primary citation: Tamborrini, D.,Wang, Z.,Wagner, T.,Tacke, S.,Stabrin, M.,Grange, M.,Kho, A.L.,Rees, M.,Bennett, P.,Gautel, M.,Raunser, S.; Structure of the native myosin filament in the relaxed cardiac sarcomere.; Nature, 623:863-871, 2023; PubMed: 37914933; DOI: 10.1038/s41586-023-06690-5

Experimental method

ELECTRON MICROSCOPY (18 Å)