7BWA

Cryo-EM Structure for the Ectodomain of the Full-length Human Insulin Receptor in Complex with 2 Insulin

Summary for 7BWA

• Entry DOI: 10.2210/pdb7bwa/pdb
• Related: 7BW7 7BW8
• EMDB information: 30225 30227 30229 30230 30231
• Descriptor: Insulin receptor, Insulin fusion (2 entities in total)
• Functional Keywords: human insulin receptor, full-length, ectodomain, insulin, conformation., signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 324990.09

Authors

Yu, D.,Zhang, X.,Sun, J.,Li, X.,Wu, Z.,Han, X.,Fan, C.,Ma, Y.,Ouyang, Q.,Wang, T. (deposition date: 2020-04-14, release date: 2021-04-14)

• Primary citation: Yu, D.,Zhang, X.,Sun, J.,Li, X.,Wu, Z.,Han, X.,Fan, C.,Ma, Y.,Ouyang, Q.,Wang, T.; Insulin Binding Induced the Ectodomain Conformational Dynamics in the Full-length Human Insulin Receptor; To Be Published,

Experimental method

ELECTRON MICROSCOPY (4.9 Å)