7BW7

Cryo-EM Structure for the Ectodomain of the Full-length Human Insulin Receptor in Complex with 1 Insulin.

Summary for 7BW7

• Entry DOI: 10.2210/pdb7bw7/pdb
• EMDB information: 30225 30227 30229
• Descriptor: Insulin receptor, Insulin fusion (2 entities in total)
• Functional Keywords: human insulin receptor, full-length, ectodomain, apo, conformation., signaling protein
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 3
• Total formula weight: 316609.56

Authors

Yu, D.,Zhang, X.,Sun, J.,Li, X.,Wu, Z.,Han, X.,Fan, C.,Ma, Y.,Ouyang, Q.,Wang, T. (deposition date: 2020-04-13, release date: 2021-04-14)

• Primary citation: Yu, D.,Zhang, X.,Sun, J.,Li, X.,Wu, Z.,Han, X.,Fan, C.,Ma, Y.,Ouyang, Q.,Wang, T.; Insulin Binding Induced the Ectodomain Conformational Dynamics in the Full-length Human Insulin Receptor; To Be Published,

Experimental method

ELECTRON MICROSCOPY (4.1 Å)