5GOG
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![BU of 5gog by Molmil](/molmil-images/mine/5gog) | Lys29-linked di-ubiquitin | Descriptor: | D-ubiquitin, Ubiquitin | Authors: | Gao, S, Pan, M, Zheng, Y. | Deposit date: | 2016-07-27 | Release date: | 2016-11-02 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.977 Å) | Cite: | Monomer/Oligomer Quasi-Racemic Protein Crystallography J.Am.Chem.Soc., 138, 2016
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3VUY
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![BU of 3vuy by Molmil](/molmil-images/mine/3vuy) | Crystal structure of A20 ZF7 in complex with linear tetraubiquitin | Descriptor: | POTASSIUM ION, Polyubiquitin-C, Tumor necrosis factor alpha-induced protein 3, ... | Authors: | Nishimasu, H, Ishitani, R, Nureki, O. | Deposit date: | 2012-07-09 | Release date: | 2013-02-13 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (1.981 Å) | Cite: | Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation Embo J., 31, 2012
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5JBY
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![BU of 5jby by Molmil](/molmil-images/mine/5jby) | Lys27-linked triubiquitin | Descriptor: | D-ubiquitin, ubiquitin | Authors: | Pan, M, Gao, S, Zheng, Y. | Deposit date: | 2016-04-14 | Release date: | 2016-07-20 | Last modified: | 2022-02-09 | Method: | X-RAY DIFFRACTION (1.987 Å) | Cite: | Structure of Lys27-linked triubiquitin To Be Published
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2G45
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![BU of 2g45 by Molmil](/molmil-images/mine/2g45) | Co-crystal structure of znf ubp domain from the deubiquitinating enzyme isopeptidase T (isot) in complex with ubiquitin | Descriptor: | CHLORIDE ION, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 5, ... | Authors: | Reyes-Turcu, F.E, Horton, J.R, Mullally, J.E, Heroux, A, Cheng, X, Wilkinson, K.D. | Deposit date: | 2006-02-21 | Release date: | 2006-04-04 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | The Ubiquitin Binding Domain ZnF UBP Recognizes the C-Terminal Diglycine Motif of Unanchored Ubiquitin. Cell(Cambridge,Mass.), 124, 2006
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2GBK
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![BU of 2gbk by Molmil](/molmil-images/mine/2gbk) | |
4IG7
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![BU of 4ig7 by Molmil](/molmil-images/mine/4ig7) | |
4WLR
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![BU of 4wlr by Molmil](/molmil-images/mine/4wlr) | Crystal Structure of mUCH37-hRPN13 CTD-hUb complex | Descriptor: | Polyubiquitin-B, Proteasomal ubiquitin receptor ADRM1, Ubiquitin carboxyl-terminal hydrolase isozyme L5 | Authors: | Hemmis, C.W, Hill, C.P, VanderLinden, R, Whitby, F.G. | Deposit date: | 2014-10-07 | Release date: | 2015-03-04 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (1.997 Å) | Cite: | Structural Basis for the Activation and Inhibition of the UCH37 Deubiquitylase. Mol.Cell, 57, 2015
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5LRW
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![BU of 5lrw by Molmil](/molmil-images/mine/5lrw) | Structure of Cezanne/OTUD7B OTU domain bound to ubiquitin | Descriptor: | GLYCEROL, OTU domain-containing protein 7B, Polyubiquitin-B | Authors: | Mevissen, T.E.T, Kulathu, Y, Mulder, M.P.C, Geurink, P.P, Maslen, S.L, Gersch, M, Elliott, P.R, Burke, J.E, van Tol, B.D.M, Akutsu, M, El Oualid, F, Kawasaki, M, Freund, S.M.V, Ovaa, H, Komander, D. | Deposit date: | 2016-08-22 | Release date: | 2016-10-19 | Last modified: | 2017-09-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase Cezanne. Nature, 538, 2016
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8T48
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![BU of 8t48 by Molmil](/molmil-images/mine/8t48) | |
1S1Q
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![BU of 1s1q by Molmil](/molmil-images/mine/1s1q) | TSG101(UEV) domain in complex with Ubiquitin | Descriptor: | ACETIC ACID, COPPER (II) ION, SULFATE ION, ... | Authors: | Sundquist, W.I, Schubert, H.L, Kelly, B.N, Hill, G.C, Holton, J.M, Hill, C.P. | Deposit date: | 2004-01-07 | Release date: | 2004-05-04 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Ubiquitin recognition by the human TSG101 protein Mol.Cell, 13, 2004
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7RMA
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![BU of 7rma by Molmil](/molmil-images/mine/7rma) | Structure of the fourth UIM (Ubiquitin Interacting Motif) of ANKRD13D in complex with a high affinity UbV (Ubiquitin Variant) | Descriptor: | Ankyrin repeat domain-containing protein 13D, SODIUM ION, SULFATE ION, ... | Authors: | Singer, A.U, Manczyk, N, Veggiani, G, Sicheri, F, Sidhu, S.S. | Deposit date: | 2021-07-27 | Release date: | 2022-05-11 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Panel of Engineered Ubiquitin Variants Targeting the Family of Human Ubiquitin Interacting Motifs. Acs Chem.Biol., 17, 2022
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5V1Z
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![BU of 5v1z by Molmil](/molmil-images/mine/5v1z) | Crystal structure of the RPN13 PRU-RPN2 (932-953)-ubiquitin complex | Descriptor: | 26S proteasome non-ATPase regulatory subunit 1, Proteasomal ubiquitin receptor ADRM1, Ubiquitin | Authors: | Hemmis, C.W, VanderLinden, R.T, Yao, T, Robinson, H, Hill, C.P. | Deposit date: | 2017-03-02 | Release date: | 2017-05-03 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure and energetics of pairwise interactions between proteasome subunits RPN2, RPN13, and ubiquitin clarify a substrate recruitment mechanism. J. Biol. Chem., 292, 2017
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2GBR
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![BU of 2gbr by Molmil](/molmil-images/mine/2gbr) | Crystal Structure of the 35-36 MoaD Insertion Mutant of Ubiquitin | Descriptor: | CADMIUM ION, Ubiquitin | Authors: | Ferraro, D.M, Ferraro, D.J, Ramaswamy, S, Robertson, A.D. | Deposit date: | 2006-03-10 | Release date: | 2006-05-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structures of Ubiquitin Insertion Mutants Support Site-specific Reflex Response to Insertions Hypothesis. J.Mol.Biol., 359, 2006
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5JG6
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![BU of 5jg6 by Molmil](/molmil-images/mine/5jg6) | APC11-Ubv shows role of noncovalent RING-Ubiquitin interactions in processive multiubiquitination and Ubiquitin chain elongation by APC/C | Descriptor: | Anaphase-promoting complex subunit 11, Polyubiquitin-B, ZINC ION | Authors: | Brown, N.G, Zhang, W, Yu, S, Miller, D.J, Sidhu, S.S, Schulman, B.A. | Deposit date: | 2016-04-19 | Release date: | 2016-06-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.0013 Å) | Cite: | Dual RING E3 Architectures Regulate Multiubiquitination and Ubiquitin Chain Elongation by APC/C. Cell, 165, 2016
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5YDR
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![BU of 5ydr by Molmil](/molmil-images/mine/5ydr) | Structure of DNMT1 RFTS domain in complex with ubiquitin | Descriptor: | DNA (cytosine-5)-methyltransferase 1, PHOSPHATE ION, Polyubiquitin-B, ... | Authors: | Qian, C. | Deposit date: | 2017-09-14 | Release date: | 2018-02-21 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.003 Å) | Cite: | Structural and mechanistic insights into UHRF1-mediated DNMT1 activation in the maintenance DNA methylation. Nucleic Acids Res., 46, 2018
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4V3K
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![BU of 4v3k by Molmil](/molmil-images/mine/4v3k) | RNF38-UbcH5B-UB complex | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, E3 UBIQUITIN-PROTEIN LIGASE RNF38, ... | Authors: | Buetow, L, Gabrielsen, M, Anthony, N.G, Dou, H, Patel, A, Aitkenhead, H, Sibbet, G.J, Smith, B.O, Huang, D.T. | Deposit date: | 2014-10-20 | Release date: | 2015-04-08 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Activation of a Primed Ring E3-E2-Ubiquitin Complex by Non-Covalent Ubiquitin. Mol.Cell, 58, 2015
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4FJV
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![BU of 4fjv by Molmil](/molmil-images/mine/4fjv) | Crystal Structure of Human Otubain2 and Ubiquitin Complex | Descriptor: | ETHANAMINE, GLYCEROL, Polyubiquitin-C, ... | Authors: | Altun, M, Walter, T.S, Kramer, H.B, Iphofer, A, David, Y, Komsany, A, Ternette, N, Nicholson, B, Navon, A, Stuart, D.I, Ren, J, Kessler, B.M. | Deposit date: | 2012-06-12 | Release date: | 2013-06-12 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.047 Å) | Cite: | The human otubain2-ubiquitin structure provides insights into the cleavage specificity of poly-ubiquitin-linkages. Plos One, 10, 2015
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6K9P
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![BU of 6k9p by Molmil](/molmil-images/mine/6k9p) | Structure of Deubiquitinase | Descriptor: | Ubiquitin, Ubiquitin thioesterase | Authors: | Lu, L.N, Liu, L, Wang, F. | Deposit date: | 2019-06-17 | Release date: | 2020-06-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.047 Å) | Cite: | Met1-specific motifs conserved in OTUB subfamily of green plants enable rice OTUB1 to hydrolyse Met1 ubiquitin chains Nat Commun, 13, 2022
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7OJE
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![BU of 7oje by Molmil](/molmil-images/mine/7oje) | Crystal structure of the covalent complex between Tribolium castaneum deubiquitinase ZUP and Ubiquitin-PA | Descriptor: | 1,2-ETHANEDIOL, CITRIC ACID, Lys-63-specific deubiquitinase ZUFSP, ... | Authors: | Pichlo, C, Hermanns, T, Hofmann, K, Baumann, U. | Deposit date: | 2021-05-14 | Release date: | 2022-02-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | A structural basis for the diverse linkage specificities within the ZUFSP deubiquitinase family. Nat Commun, 13, 2022
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7AI1
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![BU of 7ai1 by Molmil](/molmil-images/mine/7ai1) | |
7MIC
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![BU of 7mic by Molmil](/molmil-images/mine/7mic) | Maize rayado fino virus protease in complex with Ubiquitin | Descriptor: | 3-AMINOPROPANE, GLYCEROL, RNA replication protein, ... | Authors: | Patel, A, Mark, B.L. | Deposit date: | 2021-04-16 | Release date: | 2021-07-21 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.09 Å) | Cite: | The endopeptidase of the maize-affecting Marafivirus type member maize rayado fino virus doubles as a deubiquitinase. J.Biol.Chem., 297, 2021
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6P5B
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![BU of 6p5b by Molmil](/molmil-images/mine/6p5b) | Crystal Structure of MavC in Complex with Ub-UbE2N | Descriptor: | MavC, Ubiquitin, Ubiquitin-conjugating enzyme E2 N | Authors: | Puvar, K, Iyer, S, Negron Teron, K.I, Das, C. | Deposit date: | 2019-05-30 | Release date: | 2020-05-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.099 Å) | Cite: | Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination. Nat Commun, 11, 2020
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6QML
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![BU of 6qml by Molmil](/molmil-images/mine/6qml) | UCHL3 in complex with synthetic, K27-linked diubiquitin | Descriptor: | 1,2-ETHANEDIOL, BROMIDE ION, CHLORIDE ION, ... | Authors: | Murachelli, A.G, Sixma, T.K. | Deposit date: | 2019-02-07 | Release date: | 2020-02-26 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | K27-Linked Diubiquitin Inhibits UCHL3 via an Unusual Kinetic Trap. Cell Chem Biol, 28, 2021
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8FTQ
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![BU of 8ftq by Molmil](/molmil-images/mine/8ftq) | Crystal structure of hRpn13 Pru domain in complex with Ubiquitin and XL44 | Descriptor: | N-(3-{[(3R)-5-fluoro-2-oxo-2,3-dihydro-1H-indol-3-yl]methyl}phenyl)-4-methoxybenzamide, Proteasomal ubiquitin receptor ADRM1, Ubiquitin | Authors: | Walters, K.J, Lu, X, Chandravanshi, M. | Deposit date: | 2023-01-13 | Release date: | 2024-03-27 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A structure-based designed small molecule depletes hRpn13 Pru and a select group of KEN box proteins. Nat Commun, 15, 2024
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6JB7
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![BU of 6jb7 by Molmil](/molmil-images/mine/6jb7) | Crystal structure of Ub-conjugated Ube2K C92K&K97A mutant (isopeptide linkage), 2.1 A resolution | Descriptor: | Ubiquitin, Ubiquitin-conjugating enzyme E2 K | Authors: | Lee, J.-G, Youn, H.-S, Lee, Y, An, J.Y, Park, K.R, Kang, J.Y, Mun, S.A, Park, J, Park, T, Jin, M.W, Yang, J, Eom, S.H. | Deposit date: | 2019-01-25 | Release date: | 2019-03-20 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal structure of Ub-conjugated Ube2K C92K&K97A mutant (isopeptide linkage), 2.1 A resolution To Be Published
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