Crystal structure of A20 ZF7 in complex with linear tetraubiquitin

Summary for 3VUY

Related3VUW 3VUX
DescriptorPolyubiquitin-C, Tumor necrosis factor alpha-induced protein 3, ZINC ION, ... (5 entities in total)
Functional Keywordszinc finger, protein binding-metal binding protein complex, protein binding/metal binding protein
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm. A20p50: Cytoplasm P0CG48
Ubiquitin: Cytoplasm (By similarity) P21580
Total number of polymer chains6
Total molecular weight37973.66
Nishimasu, H.,Ishitani, R.,Nureki, O. (deposition date: 2012-07-09, release date: 2013-02-13)
Primary citation
Tokunaga, F.,Nishimasu, H.,Ishitani, R.,Goto, E.,Noguchi, T.,Mio, K.,Kamei, K.,Ma, A.,Iwai, K.,Nureki, O.
Specific recognition of linear polyubiquitin by A20 zinc finger 7 is involved in NF-kappaB regulation
Embo J., 31:3856-3870, 2012
PubMed: 23032187 (PDB entries with the same primary citation)
DOI: 10.1038/emboj.2012.241
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.244402.5%0.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report