3VUY

Crystal structure of A20 ZF7 in complex with linear tetraubiquitin

Functional Information from GO Data

Chain	GOid	namespace	contents
D	0003677	molecular_function	DNA binding
D	0008270	molecular_function	zinc ion binding
E	0003677	molecular_function	DNA binding
E	0008270	molecular_function	zinc ion binding
F	0003677	molecular_function	DNA binding
F	0008270	molecular_function	zinc ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 801

Chain	Residue
D	CYS762
D	CYS767
D	CYS779
D	CYS782

---

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE K D 802

Chain	Residue
D	CYS762
D	ALA764
D	CYS767

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN F 801

Chain	Residue
F	CYS779
F	CYS782
F	CYS762
F	CYS767

---

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE K F 802

Chain	Residue
F	CYS762
F	ALA764
F	CYS767

---

site_id	AC5
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN E 801

Chain	Residue
E	CYS762
E	CYS767
E	CYS779
E	CYS782

---

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE K E 802

Chain	Residue
E	CYS762
E	ALA764
E	CYS767

---

Functional Information from PROSITE/UniProt

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD

Chain	Residue	Details
A	LYS27-ASP52

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	12
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00451

Chain	Residue	Details
D	CYS762
E	CYS767
E	CYS779
E	CYS782
D	CYS767
D	CYS779
D	CYS782
F	CYS762
F	CYS767
F	CYS779
F	CYS782
E	CYS762

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	SITE: Essential for function

Chain	Residue	Details
A	HIS68
C	HIS68
B	HIS68

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	MOD_RES: Phosphoserine; by PINK1 => ECO:0000269|PubMed:24660806, ECO:0000269|PubMed:24751536, ECO:0000269|PubMed:24784582, ECO:0000269|PubMed:25527291

Chain	Residue	Details
A	SER65
C	SER65
B	SER65

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	MOD_RES: (Microbial infection) ADP-ribosylthreonine => ECO:0000269|PubMed:32330457

Chain	Residue	Details
A	THR66
C	THR66
B	THR66

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	MOD_RES: ADP-ribosylglycine => ECO:0000269|PubMed:28525742

Chain	Residue	Details
A	GLY76
C	GLY76
B	GLY76

---

site_id	SWS_FT_FI6
Number of Residues	3
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603

Chain	Residue	Details
A	LYS6
C	LYS6
B	LYS6

---

site_id	SWS_FT_FI7
Number of Residues	6
Details	CROSSLNK: Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins)

Chain	Residue	Details
A	GLY76
C	GLY76
B	GLY76

---

site_id	SWS_FT_FI8
Number of Residues	6
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16443603, ECO:0000269|PubMed:16543144

Chain	Residue	Details
A	LYS11
A	LYS48
C	LYS11
C	LYS48
B	LYS11
B	LYS48

---

site_id	SWS_FT_FI9
Number of Residues	3
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000305|PubMed:15466860

Chain	Residue	Details
A	LYS27
C	LYS27
B	LYS27

---

site_id	SWS_FT_FI10
Number of Residues	3
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:25752573, ECO:0000269|PubMed:25752577, ECO:0000269|PubMed:34239127

Chain	Residue	Details
A	LYS29
C	LYS29
B	LYS29

---

site_id	SWS_FT_FI11
Number of Residues	3
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:25752577

Chain	Residue	Details
A	LYS33
C	LYS33
B	LYS33

---

site_id	SWS_FT_FI12
Number of Residues	3
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:16543144, ECO:0000269|PubMed:18719106

Chain	Residue	Details
A	LYS63
C	LYS63
B	LYS63

---