Crystal Structure of mUCH37-hRPN13 CTD-hUb complex

Summary for 4WLR

Related4WLP 4WLQ
DescriptorUbiquitin carboxyl-terminal hydrolase isozyme L5, Proteasomal ubiquitin receptor ADRM1, Polyubiquitin-B, ... (4 entities in total)
Functional Keywordsuch37 rpn13 proteasome ino80 dub, protein binding
Biological sourceMus musculus (Mouse)
Total number of polymer chains3
Total molecular weight56829.67
Hemmis, C.W.,Hill, C.P.,VanderLinden, R.,Whitby, F.G. (deposition date: 2014-10-07, release date: 2015-03-04, Last modification date: 2019-12-04)
Primary citation
VanderLinden, R.T.,Hemmis, C.W.,Schmitt, B.,Ndoja, A.,Whitby, F.G.,Robinson, H.,Cohen, R.E.,Yao, T.,Hill, C.P.
Structural Basis for the Activation and Inhibition of the UCH37 Deubiquitylase.
Mol.Cell, 57:901-911, 2015
PubMed: 25702872 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2015.01.016
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.228200.5%13.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report