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PDB: 17 results

6J99
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BU of 6j99 by Molmil
Cryo-EM structure of human DOT1L in complex with an H2B-monoubiquitinated nucleosome
Descriptor: DNA (144-MER), DNA (145-MER), Histone H2A, ...
Authors:Yao, T, Huang, J.
Deposit date:2019-01-22
Release date:2019-02-27
Last modified:2019-04-10
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis of the crosstalk between histone H2B monoubiquitination and H3 lysine 79 methylation on nucleosome.
Cell Res., 29, 2019
3QRI
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BU of 3qri by Molmil
The crystal structure of human abl1 kinase domain in complex with DCC-2036
Descriptor: 4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide, SODIUM ION, Tyrosine-protein kinase ABL1
Authors:Chan, W.W, Wise, S.C, Kaufman, M.D, Ahn, Y.M, Ensinger, C.L, Haack, T, Hood, M.M, Jones, J, Lord, J.W, Lu, W.P, Miller, D, Patt, W.C, Smith, B.D, Petillo, P.A, Rutkoski, T.J, Telikepalli, H, Vogeti, L, Yao, T, Chun, L, Clark, R, Evangelista, P, Gavrilescu, L.C, Lazarides, K, Zaleskas, V.M, Stewart, L.J, Van Etten, R.A, Flynn, D.L.
Deposit date:2011-02-18
Release date:2011-06-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Conformational Control Inhibition of the BCR-ABL1 Tyrosine Kinase, Including the Gatekeeper T315I Mutant, by the Switch-Control Inhibitor DCC-2036.
Cancer Cell, 19, 2011
3QRJ
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BU of 3qrj by Molmil
The crystal structure of human abl1 kinase domain T315I mutant in complex with DCC-2036
Descriptor: 4-[4-({[3-tert-butyl-1-(quinolin-6-yl)-1H-pyrazol-5-yl]carbamoyl}amino)-3-fluorophenoxy]-N-methylpyridine-2-carboxamide, Tyrosine-protein kinase ABL1
Authors:Chan, W.W, Wise, S.C, Kaufman, M.D, Ahn, Y.M, Ensinger, C.L, Haack, T, Hood, M.M, Jones, J, Lord, J.W, Lu, W.P, Miller, D, Patt, W.C, Smith, B.D, Petillo, P.A, Rutkoski, T.J, Telikepalli, H, Vogeti, L, Yao, T, Chun, L, Clark, R, Evangelista, P, Gavrilescu, L.C, Lazarides, K, Zaleskas, V.M, Stewart, L.J, Van Etten, R.A, Flynn, D.L.
Deposit date:2011-02-18
Release date:2011-06-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.82 Å)
Cite:Conformational Control Inhibition of the BCR-ABL1 Tyrosine Kinase, Including the Gatekeeper T315I Mutant, by the Switch-Control Inhibitor DCC-2036.
Cancer Cell, 19, 2011
3QRK
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BU of 3qrk by Molmil
The crystal structure of human abl1 kinase domain in complex with DP-987
Descriptor: (3S)-6-(3-tert-butyl-5-{[(2,3-dichlorophenyl)carbamoyl]amino}-1H-pyrazol-1-yl)-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid, Tyrosine-protein kinase ABL1
Authors:Chan, W.W, Wise, S.C, Kaufman, M.D, Ahn, Y.M, Ensinger, C.L, Haack, T, Hood, M.M, Jones, J, Lord, J.W, Lu, W.P, Miller, D, Patt, W.C, Smith, B.D, Petillo, P.A, Rutkoski, T.J, Telikepalli, H, Vogeti, L, Yao, T, Chun, L, Clark, R, Evangelista, P, Gavrilescu, L.C, Lazarides, K, Zaleskas, V.M, Stewart, L.J, Van Etten, R.A, Flynn, D.L.
Deposit date:2011-02-18
Release date:2011-06-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Conformational Control Inhibition of the BCR-ABL1 Tyrosine Kinase, Including the Gatekeeper T315I Mutant, by the Switch-Control Inhibitor DCC-2036.
Cancer Cell, 19, 2011
1NB8
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BU of 1nb8 by Molmil
Structure of the catalytic domain of USP7 (HAUSP)
Descriptor: Ubiquitin carboxyl-terminal hydrolase 7
Authors:Hu, M, Li, P, Li, M, Li, W, Yao, T, Wu, J.-W, Gu, W, Cohen, R.E, Shi, Y.
Deposit date:2002-12-02
Release date:2003-01-07
Last modified:2018-04-04
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde
Cell(Cambridge,Mass.), 111, 2002
1NBF
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BU of 1nbf by Molmil
Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde
Descriptor: Ubiquitin aldehyde, Ubiquitin carboxyl-terminal hydrolase 7
Authors:Hu, M, Li, P, Li, M, Li, W, Yao, T, Wu, J.-W, Gu, W, Cohen, R.E, Shi, Y.
Deposit date:2002-12-02
Release date:2003-01-07
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of a UBP-family deubiquitinating enzyme in isolation and in complex with ubiquitin aldehyde
Cell(Cambridge,Mass.), 111, 2002
3MHS
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BU of 3mhs by Molmil
Structure of the SAGA Ubp8/Sgf11/Sus1/Sgf73 DUB module bound to ubiquitin aldehyde
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Protein SUS1, ...
Authors:Samara, N.L, Datta, A.B, Berndsen, C.E, Zhang, X, Yao, T, Cohen, R.E, Wolberger, C.
Deposit date:2010-04-08
Release date:2010-04-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.89 Å)
Cite:Structural insights into the assembly and function of the SAGA deubiquitinating module.
Science, 328, 2010
3MHH
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BU of 3mhh by Molmil
Structure of the SAGA Ubp8/Sgf11/Sus1/Sgf73 DUB module
Descriptor: Protein SUS1, SAGA-associated factor 11, SAGA-associated factor 73, ...
Authors:Samara, N.L, Datta, A.B, Berndsen, C.E, Zhang, X, Yao, T, Cohen, R.E, Wolberger, C.
Deposit date:2010-04-08
Release date:2010-04-21
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Structural insights into the assembly and function of the SAGA deubiquitinating module.
Science, 328, 2010
5V1Y
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BU of 5v1y by Molmil
Crystal structure of the ternary RPN13 PRU-RPN2 (940-953)-ubiquitin complex
Descriptor: 26S proteasome non-ATPase regulatory subunit 1, Proteasomal ubiquitin receptor ADRM1, Ubiquitin
Authors:Hemmis, C.W, VanderLinden, R.T, Yao, T, Robinson, H, Hill, C.P.
Deposit date:2017-03-02
Release date:2017-05-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.421 Å)
Cite:Structure and energetics of pairwise interactions between proteasome subunits RPN2, RPN13, and ubiquitin clarify a substrate recruitment mechanism.
J. Biol. Chem., 292, 2017
5V1Z
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BU of 5v1z by Molmil
Crystal structure of the RPN13 PRU-RPN2 (932-953)-ubiquitin complex
Descriptor: 26S proteasome non-ATPase regulatory subunit 1, Proteasomal ubiquitin receptor ADRM1, Ubiquitin
Authors:Hemmis, C.W, VanderLinden, R.T, Yao, T, Robinson, H, Hill, C.P.
Deposit date:2017-03-02
Release date:2017-05-03
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structure and energetics of pairwise interactions between proteasome subunits RPN2, RPN13, and ubiquitin clarify a substrate recruitment mechanism.
J. Biol. Chem., 292, 2017
2DQ4
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BU of 2dq4 by Molmil
Crystal structure of threonine 3-dehydrogenase
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, L-threonine 3-dehydrogenase, ZINC ION
Authors:Omi, R, Yao, T, Goto, M, Miyahara, I, Hirotsu, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
Deposit date:2006-05-19
Release date:2007-06-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of threonine 3-dehydrogenase
To be Published
2EJV
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BU of 2ejv by Molmil
Crystal structure of threonine 3-dehydrogenase complexed with NAD+
Descriptor: L-threonine 3-dehydrogenase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ZINC ION
Authors:Omi, R, Yao, T, Goto, M, Miyahara, I, Hirotsu, K.
Deposit date:2007-03-20
Release date:2008-03-25
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.55 Å)
Cite:Crystal structure of threonine 3-dehydrogenase
To be Published
6KIX
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BU of 6kix by Molmil
Cryo-EM structure of human MLL1-NCP complex, binding mode1
Descriptor: DNA (145-MER), GLUTAMINE, Histone H2A, ...
Authors:Huang, J, Xue, H, Yao, T.
Deposit date:2019-07-20
Release date:2019-09-11
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis of nucleosome recognition and modification by MLL methyltransferases.
Nature, 573, 2019
6KIV
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BU of 6kiv by Molmil
Cryo-EM structure of human MLL1-ubNCP complex (4.0 angstrom)
Descriptor: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Huang, J, Xue, H, Yao, T.
Deposit date:2019-07-20
Release date:2019-09-11
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of nucleosome recognition and modification by MLL methyltransferases.
Nature, 573, 2019
6KIZ
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BU of 6kiz by Molmil
Cryo-EM structure of human MLL1-NCP complex, binding mode2
Descriptor: DNA (145-MER), Histone H2A, Histone H2B 1.1, ...
Authors:Huang, J, Xue, H, Yao, T.
Deposit date:2019-07-20
Release date:2019-09-11
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4.5 Å)
Cite:Structural basis of nucleosome recognition and modification by MLL methyltransferases.
Nature, 573, 2019
6KIU
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BU of 6kiu by Molmil
Cryo-EM structure of human MLL1-ubNCP complex (3.2 angstrom)
Descriptor: DNA (145-MER), GLUTAMINE, Histone H2A, ...
Authors:Huang, J, Xue, H, Yao, T.
Deposit date:2019-07-20
Release date:2019-09-11
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Structural basis of nucleosome recognition and modification by MLL methyltransferases.
Nature, 573, 2019
6KIW
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BU of 6kiw by Molmil
Cryo-EM structure of human MLL3-ubNCP complex (4.0 angstrom)
Descriptor: DNA (144-MER), DNA (145-MER), Histone H2A, ...
Authors:Huang, J, Xue, H, Yao, T.
Deposit date:2019-07-20
Release date:2019-09-11
Last modified:2024-03-27
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Structural basis of nucleosome recognition and modification by MLL methyltransferases.
Nature, 573, 2019

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