Structure of the SAGA Ubp8/Sgf11/Sus1/Sgf73 DUB module bound to ubiquitin aldehyde

Summary for 3MHS

DescriptorUbiquitin carboxyl-terminal hydrolase 8, Protein SUS1, SAGA-associated factor 11, ... (9 entities in total)
Functional Keywordsmulti-protein complex, hydrolase-transcription regulator-protein binding complex, acetylation, cytoplasm, isopeptide bond, nucleus, phosphoprotein, ubl conjugation, hydrolase/transcription regulator/protein binding
Biological sourceSaccharomyces cerevisiae (brewer's yeast,lager beer yeast,yeast)
Cellular locationNucleus (Probable) P50102 Q03067 P62988
Nucleus, nucleoplasm Q6WNK7
Total number of polymer chains5
Total molecular weight96488.29
Samara, N.L.,Datta, A.B.,Berndsen, C.E.,Zhang, X.,Yao, T.,Cohen, R.E.,Wolberger, C. (deposition date: 2010-04-08, release date: 2010-04-21, Last modification date: 2011-07-13)
Primary citation
Samara, N.L.,Datta, A.B.,Berndsen, C.E.,Zhang, X.,Yao, T.,Cohen, R.E.,Wolberger, C.
Structural insights into the assembly and function of the SAGA deubiquitinating module.
Science, 328:1025-1029, 2010
PubMed: 20395473 (PDB entries with the same primary citation)
DOI: 10.1126/science.1190049
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.2151304.1%8.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report