7AI1
Crystal structure of human MDM2-G443T RING domain homodimer bound to UbcH5B-Ub (Crystal form 2)
This is a non-PDB format compatible entry.
Summary for 7AI1
Entry DOI | 10.2210/pdb7ai1/pdb |
Related | 6SQO |
Descriptor | E3 ubiquitin-protein ligase Mdm2, Ubiquitin-conjugating enzyme E2 D2, Polyubiquitin-B, ... (7 entities in total) |
Functional Keywords | ubiquitin ligase, ring e3, ligase |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 6 |
Total formula weight | 68663.55 |
Authors | Magnussen, H.M.,Huang, D.T. (deposition date: 2020-09-25, release date: 2021-01-20, Last modification date: 2024-05-01) |
Primary citation | Magnussen, H.M.,Huang, D.T. Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant. J.Mol.Biol., 433:166807-166807, 2021 Cited by PubMed: 33450248DOI: 10.1016/j.jmb.2021.166807 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.07 Å) |
Structure validation
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