7AI1

Crystal structure of human MDM2-G443T RING domain homodimer bound to UbcH5B-Ub (Crystal form 2)

This is a non-PDB format compatible entry.

Summary for 7AI1

• Entry DOI: 10.2210/pdb7ai1/pdb
• Related: 6SQO
• Descriptor: E3 ubiquitin-protein ligase Mdm2, Ubiquitin-conjugating enzyme E2 D2, Polyubiquitin-B, ... (7 entities in total)
• Functional Keywords: ubiquitin ligase, ring e3, ligase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 6
• Total formula weight: 68663.55

Authors

Magnussen, H.M.,Huang, D.T. (deposition date: 2020-09-25, release date: 2021-01-20, Last modification date: 2021-02-10)

• Primary citation: Magnussen, H.M.,Huang, D.T.; Identification of a Catalytic Active but Non-Aggregating MDM2 RING Domain Variant.; J.Mol.Biol., 433:166807-166807, 2021; PubMed: 33450248; DOI: 10.1016/j.jmb.2021.166807

Experimental method

X-RAY DIFFRACTION (2.07 Å)