7RMA

Structure of the fourth UIM (Ubiquitin Interacting Motif) of ANKRD13D in complex with a high affinity UbV (Ubiquitin Variant)

Summary for 7RMA

• Entry DOI: 10.2210/pdb7rma/pdb
• Related: 6NJG
• Descriptor: Ubiquitin Variant, Ankyrin repeat domain-containing protein 13D, SULFATE ION, ... (5 entities in total)
• Functional Keywords: ubiquitin-interacting motif, uim, ubiquitin variant, protein engineering, protein recognition, strand-exchange dimer, protein binding
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 2
• Total formula weight: 12393.89

Authors

Singer, A.U.,Manczyk, N.,Veggiani, G.,Sicheri, F.,Sidhu, S.S. (deposition date: 2021-07-27, release date: 2022-05-11, Last modification date: 2023-10-18)

• Primary citation: Veggiani, G.,Yates, B.P.,Martyn, G.D.,Manczyk, N.,Singer, A.U.,Kurinov, I.,Sicheri, F.,Sidhu, S.S.; Panel of Engineered Ubiquitin Variants Targeting the Family of Human Ubiquitin Interacting Motifs.; Acs Chem.Biol., 17:941-956, 2022; PubMed: 35385646; DOI: 10.1021/acschembio.2c00089

Experimental method

X-RAY DIFFRACTION (2 Å)