8R55
| Bacillus subtilis MutS2-collided disome complex (collided 70S) | Descriptor: | 16S rRNA (1533-MER), 23S RNA (2887-MER), 30S ribosomal protein S10, ... | Authors: | Park, E, Mackens-Kiani, T, Berhane, R, Esser, H, Erdenebat, C, Burroughs, A.M, Berninghausen, O, Aravind, L, Beckmann, R, Green, R, Buskirk, A.R. | Deposit date: | 2023-11-16 | Release date: | 2024-01-17 | Last modified: | 2024-02-28 | Method: | ELECTRON MICROSCOPY (3.57 Å) | Cite: | B. subtilis MutS2 splits stalled ribosomes into subunits without mRNA cleavage. Embo J., 43, 2024
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8A6W
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6AO3
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1BU1
| SRC FAMILY KINASE HCK SH3 DOMAIN | Descriptor: | PROTEIN (HEMOPOIETIC CELL KINASE) | Authors: | Arold, S, Franken, P, Dumas, C. | Deposit date: | 1998-09-09 | Release date: | 1998-11-11 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | RT loop flexibility enhances the specificity of Src family SH3 domains for HIV-1 Nef. Biochemistry, 37, 1998
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6V65
| Crystal structure of KRAS(GMPPNP)-NF1(GRD)-SPRED1 complex | Descriptor: | FORMIC ACID, GTPase KRas, MAGNESIUM ION, ... | Authors: | Yan, W, Simanshu, D.K. | Deposit date: | 2019-12-04 | Release date: | 2020-07-15 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.763 Å) | Cite: | Structural Insights into the SPRED1-Neurofibromin-KRAS Complex and Disruption of SPRED1-Neurofibromin Interaction by Oncogenic EGFR. Cell Rep, 32, 2020
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5J7K
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1BUQ
| SOLUTION STRUCTURE OF DELTA-5-3-KETOSTEROID ISOMERASE COMPLEXED WITH THE STEROID 19-NORTESTOSTERONE-HEMISUCCINATE | Descriptor: | PROTEIN (3-KETOSTEROID ISOMERASE-19-NORTESTOSTERONE-HEMISUCCINATE), SUCCINIC ACID MONO-(13-METHYL-3-OXO-2,3,6,7,8,9,10,11,12,13,14,15,16,17-TETRADECAHYDRO-1H-CYCLOPENTA[A]PHENANTHREN-17-YL) ESTER | Authors: | Massiah, M.A, Abeygunawardana, C, Gittis, A.G, Mildvan, A.S. | Deposit date: | 1998-09-04 | Release date: | 1999-01-20 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Solution structure of Delta 5-3-ketosteroid isomerase complexed with the steroid 19-nortestosterone hemisuccinate. Biochemistry, 37, 1998
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6JBZ
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8G94
| Structure of CD69-bound S1PR1 coupled to heterotrimeric Gi | Descriptor: | Early activation antigen CD69, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Chen, H, Li, X. | Deposit date: | 2023-02-21 | Release date: | 2023-04-19 | Last modified: | 2023-04-26 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Transmembrane protein CD69 acts as an S1PR1 agonist. Elife, 12, 2023
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6AQ7
| Structure of POM6 FAB fragment complexed with mouse PrPc | Descriptor: | 3,3',3''-phosphanetriyltripropanoic acid, GLYCEROL, Major prion protein, ... | Authors: | Baral, P.K, Swayampakula, M, James, M.N.G. | Deposit date: | 2017-08-18 | Release date: | 2018-04-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Structural characterization of POM6 Fab and mouse prion protein complex identifies key regions for prions conformational conversion. FEBS J., 285, 2018
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8A9P
| Crystal structure of CYP142 from Mycobacterium tuberculosis in complex with a fragment | Descriptor: | (3-phenyl-1,2,4-oxadiazol-5-yl)methanamine, BROMIDE ION, CHLORIDE ION, ... | Authors: | Snee, M, Katariya, M, Levy, C, Leys, D. | Deposit date: | 2022-06-29 | Release date: | 2023-07-12 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Crystal structure of CYP142 from Mycobacterium tuberculosis in complex with a fragment To Be Published
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7KHP
| Acyl-enzyme intermediate structure of SARS-CoV-2 Mpro in complex with its C-terminal autoprocessing sequence. | Descriptor: | 3C-like proteinase, DIMETHYL SULFOXIDE | Authors: | Lee, J, Worrall, L.J, Paetzel, M, Strynadka, N.C.J. | Deposit date: | 2020-10-21 | Release date: | 2020-10-28 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystallographic structure of wild-type SARS-CoV-2 main protease acyl-enzyme intermediate with physiological C-terminal autoprocessing site. Nat Commun, 11, 2020
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7ANU
| Crystal structure of Pyrococcus abyssi Pbp11 | Descriptor: | GLYCEROL, IMIDAZOLE, NICKEL (II) ION, ... | Authors: | Hogrel, G, Girard, E, Franzetti, B. | Deposit date: | 2020-10-12 | Release date: | 2021-11-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | Characterization of a small tRNA-binding protein that interacts with the archaeal proteasome complex. Mol.Microbiol., 118, 2022
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7KJ7
| Plasmodium falciparum protein Pf12p | Descriptor: | Surface protein P12p | Authors: | Dietrich, M.H, Tham, W.H. | Deposit date: | 2020-10-26 | Release date: | 2021-02-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Nanobody generation and structural characterization of Plasmodium falciparum 6-cysteine protein Pf12p. Biochem.J., 478, 2021
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2IWG
| COMPLEX BETWEEN THE PRYSPRY DOMAIN OF TRIM21 AND IGG FC | Descriptor: | 52 KDA RO PROTEIN, IG GAMMA-1 CHAIN C, alpha-L-fucopyranose, ... | Authors: | James, L.C, Keeble, A.H, Rhodes, D.A, Trowsdale, J. | Deposit date: | 2006-06-30 | Release date: | 2007-03-27 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Structural Basis for Pryspry-Mediated Tripartite Motif (Trim) Protein Function. Proc.Natl.Acad.Sci.USA, 104, 2007
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7KOE
| Electron bifurcating flavoprotein Fix/EtfABCX | Descriptor: | Electron transfer flavoprotein, alpha subunit, beta subunit, ... | Authors: | Feng, X, Li, H. | Deposit date: | 2020-11-08 | Release date: | 2021-01-20 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Cryoelectron microscopy structure and mechanism of the membrane-associated electron-bifurcating flavoprotein Fix/EtfABCX. Proc.Natl.Acad.Sci.USA, 118, 2021
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7B1X
| Crystal structure of cold-active esterase PMGL3 from permafrost metagenomic library | Descriptor: | esterase PMGL3 | Authors: | Boyko, K.M, Nikolaeva, A.Y, Petrovskaya, L.E, Kryukova, M.V, Kryukova, E.A, Korzhenevsky, D.A, Lomakina, G.Y, Novototskaya-Vlasova, K.A, Rivkina, E.M, Dolgikh, D.A, Kirpichnikov, M.P, Popov, V.O. | Deposit date: | 2020-11-25 | Release date: | 2021-11-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and Biochemical Characterization of a Cold-Active PMGL3 Esterase with Unusual Oligomeric Structure. Biomolecules, 11, 2021
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5JK7
| The X-ray structure of the DDB1-DCAF1-Vpr-UNG2 complex | Descriptor: | DNA damage-binding protein 1, Protein VPRBP, Protein Vpr, ... | Authors: | Calero, G, Ahn, J, Wu, Y. | Deposit date: | 2016-04-26 | Release date: | 2016-10-05 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (3.49 Å) | Cite: | The DDB1-DCAF1-Vpr-UNG2 crystal structure reveals how HIV-1 Vpr steers human UNG2 toward destruction. Nat.Struct.Mol.Biol., 23, 2016
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5JMC
| Receptor binding domain of Botulinum neurotoxin A in complex with rat SV2C | Descriptor: | Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2C | Authors: | Yao, G, Zhang, S, Mahrhold, S, Lam, K, Stern, D, Bagramyan, K, Perry, K, Kalkum, M, Rummel, A, Dong, M, Jin, R. | Deposit date: | 2016-04-28 | Release date: | 2016-06-15 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.64 Å) | Cite: | N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A. Nat.Struct.Mol.Biol., 23, 2016
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7AIK
| Ribonucleotide Reductase R2 protein from Aquifex aeolicus | Descriptor: | FE (II) ION, Ribonucleoside-diphosphate reductase subunit beta,Ribonucleoside-diphosphate reductase subunit beta | Authors: | Rehling, D, Scaletti, E.R, Stenmark, P. | Deposit date: | 2020-09-27 | Release date: | 2021-11-03 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural and Biochemical Investigation of Class I Ribonucleotide Reductase from the Hyperthermophile Aquifex aeolicus. Biochemistry, 61, 2022
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5MCU
| New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins (complex p53DBD-LHG2) | Descriptor: | 1,2-ETHANEDIOL, Cellular tumor antigen p53, DNA, ... | Authors: | Golovenko, D, Rozenberg, H, Shakked, Z. | Deposit date: | 2016-11-10 | Release date: | 2018-06-13 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins. Structure, 26, 2018
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6SP2
| CryoEM structure of SERINC from Drosophila melanogaster | Descriptor: | CARDIOLIPIN, Lauryl Maltose Neopentyl Glycol, Membrane protein TMS1d, ... | Authors: | Pye, V.E, Nans, A, Cherepanov, P. | Deposit date: | 2019-08-30 | Release date: | 2020-01-01 | Last modified: | 2022-03-30 | Method: | ELECTRON MICROSCOPY (3.33 Å) | Cite: | A bipartite structural organization defines the SERINC family of HIV-1 restriction factors. Nat.Struct.Mol.Biol., 27, 2020
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6BBA
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7ZZI
| Plasmodium falciparum hexokinase complexed with glucose and citrate | Descriptor: | 1,2-ETHANEDIOL, CITRIC ACID, Phosphotransferase, ... | Authors: | Fritz-Wolf, K, Dillenberger, M, Rahlfs, S, Becker, K. | Deposit date: | 2022-05-25 | Release date: | 2023-08-30 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Analysis of Plasmodium falciparum Hexokinase Provides Novel Information about Catalysis Due to a Plasmodium -Specific Insertion. Int J Mol Sci, 24, 2023
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8RZC
| SARS-CoV-2 nsp16-nsp10 in complex with SAM derivative inhibitor 11 | Descriptor: | 2'-O-methyltransferase nsp16, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 3-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methylsulfanylmethyl]-5-imidazol-1-yl-benzoic acid, ... | Authors: | Kalnins, G. | Deposit date: | 2024-02-12 | Release date: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | SARS-CoV-2 nsp16-nsp10 in complex with SAM derivative inhibitor 11 To Be Published
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