6AQ7

Structure of POM6 FAB fragment complexed with mouse PrPc

Summary for 6AQ7

• Entry DOI: 10.2210/pdb6aq7/pdb
• Descriptor: Major prion protein, POM6 FAB Heavy CHAIN, POM6 FAB light CHAIN, ... (6 entities in total)
• Functional Keywords: prion, antibody, chaperone, antigen-antibody, immune system
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 3
• Total formula weight: 61907.07

Authors

Baral, P.K.,Swayampakula, M.,James, M.N.G. (deposition date: 2017-08-18, release date: 2018-04-04, Last modification date: 2023-10-04)

• Primary citation: Baral, P.K.,Swayampakula, M.,Aguzzi, A.,James, M.N.G.; Structural characterization of POM6 Fab and mouse prion protein complex identifies key regions for prions conformational conversion.; FEBS J., 285:1701-1714, 2018; PubMed: 29569342; DOI: 10.1111/febs.14438

Experimental method

X-RAY DIFFRACTION (1.83 Å)