6AQ7
Structure of POM6 FAB fragment complexed with mouse PrPc
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Major prion protein | polymer | 122 | 14481.1 | 1 | UniProt (P04925) Pfam (PF00377) | Mus musculus (Mouse) | PrP,PrP27-30,PrP33-35C |
| 2 | B (H) | POM6 FAB Heavy CHAIN | polymer | 214 | 23203.2 | 1 | Mus musculus (Mouse) | ||
| 3 | C (L) | POM6 FAB light CHAIN | polymer | 216 | 23788.4 | 1 | Mus musculus (Mouse) | ||
| 4 | D, F (A, L) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | E (H) | 3,3',3''-phosphanetriyltripropanoic acid | non-polymer | 250.2 | 1 | Chemie (TCE) | |||
| 6 | G, H, I (A, H, L) | water | water | 18.0 | 460 | Chemie (HOH) |
Sequence modifications
A: 127 - 225 (UniProt: P04925)
| PDB | External Database | Details |
|---|---|---|
| Met 104 | - | initiating methionine |
| Gly 105 | - | expression tag |
| Ser 106 | - | expression tag |
| Ser 107 | - | expression tag |
| His 108 | - | expression tag |
| His 109 | - | expression tag |
| His 110 | - | expression tag |
| His 111 | - | expression tag |
| His 112 | - | expression tag |
| His 113 | - | expression tag |
| Ser 114 | - | expression tag |
| Ser 115 | - | expression tag |
| Gly 116 | - | expression tag |
| Leu 117 | - | expression tag |
| Val 118 | - | expression tag |
| Pro 119 | - | expression tag |
| Arg 120 | - | expression tag |
| Gly 121 | - | expression tag |
| Ser 122 | - | expression tag |
| His 123 | - | expression tag |
| Met 124 | - | expression tag |
| Gly 125 | - | expression tag |
| Gly 126 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 61472.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 434.4 | |
| All* | Total formula weight | 61907.1 |
