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1BU1

SRC FAMILY KINASE HCK SH3 DOMAIN

Summary for 1BU1
Entry DOI10.2210/pdb1bu1/pdb
DescriptorPROTEIN (HEMOPOIETIC CELL KINASE) (2 entities in total)
Functional Keywordstyrosine-protein kinase, transferase, signal transduction, sh3
Biological sourceHomo sapiens (human)
Cellular locationIsoform 1: Lysosome. Isoform 2: Cell membrane ; Lipid-anchor . Cytoplasmic vesicle, secretory vesicle: P08631
Total number of polymer chains6
Total formula weight39812.57
Authors
Arold, S.,Franken, P.,Dumas, C. (deposition date: 1998-09-09, release date: 1998-11-11, Last modification date: 2023-08-09)
Primary citationArold, S.,O'Brien, R.,Franken, P.,Strub, M.P.,Hoh, F.,Dumas, C.,Ladbury, J.E.
RT loop flexibility enhances the specificity of Src family SH3 domains for HIV-1 Nef.
Biochemistry, 37:14683-14691, 1998
Cited by
PubMed: 9778343
DOI: 10.1021/bi980989q
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

217705

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