6SP2

CryoEM structure of SERINC from Drosophila melanogaster

Summary for 6SP2

Entry DOI	10.2210/pdb6sp2/pdb
EMDB information	10277 10279
Descriptor	Membrane protein TMS1d, Lauryl Maltose Neopentyl Glycol, O-[(R)-{[(2R)-2,3-bis(octadecanoyloxy)propyl]oxy}(hydroxy)phosphoryl]-L-serine, ... (4 entities in total)
Functional Keywords	anti-retroviral, tm10, serinc fold, novel fold, membrane protein
Biological source	Drosophila melanogaster (Fruit fly)
Total number of polymer chains	6
Total formula weight	353929.39
Authors	Pye, V.E.,Nans, A.,Cherepanov, P. (deposition date: 2019-08-30, release date: 2020-01-01, Last modification date: 2022-03-30)
Primary citation	Pye, V.E.,Rosa, A.,Bertelli, C.,Struwe, W.B.,Maslen, S.L.,Corey, R.,Liko, I.,Hassall, M.,Mattiuzzo, G.,Ballandras-Colas, A.,Nans, A.,Takeuchi, Y.,Stansfeld, P.J.,Skehel, J.M.,Robinson, C.V.,Pizzato, M.,Cherepanov, P. A bipartite structural organization defines the SERINC family of HIV-1 restriction factors. Nat.Struct.Mol.Biol., 27:78-83, 2020 Cited by PubMed: 31907454 DOI: 10.1038/s41594-019-0357-0 PDB entries with the same primary citation
Experimental method	ELECTRON MICROSCOPY (3.33 Å)

Structure validation