5JMC
Receptor binding domain of Botulinum neurotoxin A in complex with rat SV2C
Summary for 5JMC
Entry DOI | 10.2210/pdb5jmc/pdb |
Related | 5JLV |
Descriptor | Botulinum neurotoxin type A, Synaptic vesicle glycoprotein 2C (3 entities in total) |
Functional Keywords | hydrolase |
Biological source | Clostridium botulinum More |
Total number of polymer chains | 8 |
Total formula weight | 259976.98 |
Authors | Yao, G.,Zhang, S.,Mahrhold, S.,Lam, K.,Stern, D.,Bagramyan, K.,Perry, K.,Kalkum, M.,Rummel, A.,Dong, M.,Jin, R. (deposition date: 2016-04-28, release date: 2016-06-15, Last modification date: 2023-09-27) |
Primary citation | Yao, G.,Zhang, S.,Mahrhold, S.,Lam, K.H.,Stern, D.,Bagramyan, K.,Perry, K.,Kalkum, M.,Rummel, A.,Dong, M.,Jin, R. N-linked glycosylation of SV2 is required for binding and uptake of botulinum neurotoxin A. Nat.Struct.Mol.Biol., 23:656-662, 2016 Cited by PubMed: 27294781DOI: 10.1038/nsmb.3245 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.64 Å) |
Structure validation
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