5MCU
New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins (complex p53DBD-LHG2)
Summary for 5MCU
Entry DOI | 10.2210/pdb5mcu/pdb |
Related | 3KZ8 5MCT 5MCV 5MCW 5MF7 5MG7 6FJ5 |
Descriptor | Cellular tumor antigen p53, DNA, ZINC ION, ... (5 entities in total) |
Functional Keywords | transcription, p53, transcription factor, dna binding, dna recognition, hoogsteen base-pairing, isoguanine, 2-oxo-adenine, transcription regulation, apoptosis, biological rhythms, cell cycle, nucleus, tumor suppressor, antigen ny-co-13, phosphoprotein |
Biological source | Homo sapiens (Human) More |
Total number of polymer chains | 3 |
Total formula weight | 51987.52 |
Authors | Golovenko, D.,Rozenberg, H.,Shakked, Z. (deposition date: 2016-11-10, release date: 2018-06-13, Last modification date: 2024-01-17) |
Primary citation | Golovenko, D.,Brauning, B.,Vyas, P.,Haran, T.E.,Rozenberg, H.,Shakked, Z. New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins. Structure, 26:1237-1250.e6, 2018 Cited by PubMed: 30057026DOI: 10.1016/j.str.2018.06.006 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.7 Å) |
Structure validation
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