1BJ1
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![BU of 1bj1 by Molmil](/molmil-images/mine/1bj1) | VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH A NEUTRALIZING ANTIBODY | Descriptor: | Fab fragment, heavy chain, light chain, ... | Authors: | Muller, Y.A, Christinger, H.W, De Vos, A.M. | Deposit date: | 1998-06-30 | Release date: | 1999-01-13 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 A resolution and mutational analysis of the interface. Structure, 6, 1998
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6LGW
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![BU of 6lgw by Molmil](/molmil-images/mine/6lgw) | Structure of Rabies virus glycoprotein in complex with neutralizing antibody 523-11 at acidic pH | Descriptor: | Glycoprotein, scFv 523-11 | Authors: | Yang, F.L, Lin, S, Ye, F, Yang, J, Qi, J.X, Chen, Z.J, Lin, X, Wang, J.C, Yue, D, Cheng, Y.W, Chen, Z.M, Chen, H, You, Y, Zhang, Z.L, Yang, Y, Yang, M, Sun, H.L, Li, Y.H, Cao, Y, Yang, S.Y, Wei, Y.Q, Gao, G.F, Lu, G.W. | Deposit date: | 2019-12-06 | Release date: | 2020-02-19 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.9037 Å) | Cite: | Structural Analysis of Rabies Virus Glycoprotein Reveals pH-Dependent Conformational Changes and Interactions with a Neutralizing Antibody. Cell Host Microbe, 27, 2020
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8RND
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![BU of 8rnd by Molmil](/molmil-images/mine/8rnd) | Cathepsin S in complex with NNPI-C10 inhibitor | Descriptor: | 1,2-ETHANEDIOL, Cathepsin S, DI(HYDROXYETHYL)ETHER, ... | Authors: | Petruzzella, A, Lau, K, Pojer, F, Oricchio, E. | Deposit date: | 2024-01-09 | Release date: | 2024-06-05 | Last modified: | 2024-06-12 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Antibody-peptide conjugates deliver covalent inhibitors blocking oncogenic cathepsins. Nat.Chem.Biol., 2024
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7JTI
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![BU of 7jti by Molmil](/molmil-images/mine/7jti) | Interphotoreceptor retinoid-binding protein (IRBP) in complex with a monoclonal antibody (F3F5 mAb5) | Descriptor: | Retinol-binding protein 3, mAb5 Fab heavy chain, mAb5 Fab light chain | Authors: | Sears, A.E, Albiez, S, Gulati, S, Wang, B, Kiser, P, Kovacik, L, Engel, A, Stahlberg, H, Palczewski, K. | Deposit date: | 2020-08-17 | Release date: | 2020-10-07 | Last modified: | 2020-12-16 | Method: | ELECTRON MICROSCOPY (7.4 Å) | Cite: | Single particle cryo-EM of the complex between interphotoreceptor retinoid-binding protein and a monoclonal antibody. Faseb J., 34, 2020
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7D4G
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![BU of 7d4g by Molmil](/molmil-images/mine/7d4g) | |
8TFH
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![BU of 8tfh by Molmil](/molmil-images/mine/8tfh) | Ricin in complex with Fab JB4 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, JB4 monoclonal antibody heavy chain, ... | Authors: | Rudolph, M.J, Mantis, N. | Deposit date: | 2023-07-11 | Release date: | 2024-04-17 | Method: | X-RAY DIFFRACTION (3.29 Å) | Cite: | Structural Basis of Antibody-Mediated Inhibition of Ricin Toxin Attachment to Host Cells. Biochemistry, 62, 2023
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1MHP
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![BU of 1mhp by Molmil](/molmil-images/mine/1mhp) | Crystal structure of a chimeric alpha1 integrin I-domain in complex with the Fab fragment of a humanized neutralizing antibody | Descriptor: | FAB FRAGMENT, light chain, Fab fragment, ... | Authors: | Karpusas, M, Taylor, F, Ferrant, J, Weinreb, P, Garber, E. | Deposit date: | 2002-08-20 | Release date: | 2003-04-15 | Last modified: | 2021-10-27 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystal Structure of the alpha 1 beta 1 Integrin I Domain in Complex with
an Antibody Fab Fragment J.Mol.Biol., 327, 2003
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5DSS
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![BU of 5dss by Molmil](/molmil-images/mine/5dss) | |
2AJ3
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![BU of 2aj3 by Molmil](/molmil-images/mine/2aj3) | Crystal Structure of a Cross-Reactive HIV-1 Neutralizing CD4-Binding Site Antibody Fab m18 | Descriptor: | Fab m18, Heavy Chain, Light Chain, ... | Authors: | Prabakaran, P, Gan, J, Wu, Y.Q, Zhang, M.Y, Dimitrov, D.S, Ji, X. | Deposit date: | 2005-08-01 | Release date: | 2006-03-28 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.03 Å) | Cite: | Structural mimicry of CD4 by a cross-reactive HIV-1 neutralizing antibody with CDR-H2 and H3 containing unique motifs. J.Mol.Biol., 357, 2006
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5YD3
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![BU of 5yd3 by Molmil](/molmil-images/mine/5yd3) | Crystal structure of the scFv antibody 4B08 with epitope peptide | Descriptor: | Epitope peptide, GLYCEROL, SULFATE ION, ... | Authors: | Caaveiro, J.M.M, Miyanabe, K, Tsumoto, K. | Deposit date: | 2017-09-11 | Release date: | 2018-06-06 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Intramolecular H-bonds govern the recognition of a flexible peptide by an antibody J. Biochem., 164, 2018
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3EYF
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![BU of 3eyf by Molmil](/molmil-images/mine/3eyf) | Crystal structure of anti-human cytomegalovirus antibody 8f9 plus gB peptide | Descriptor: | 8f9 Fab, AD-2, GLYCEROL, ... | Authors: | Thomson, C.A, Bryson, S, McLean, G.R, Creagh, A.L, Pai, E.F, Schrader, J.W. | Deposit date: | 2008-10-20 | Release date: | 2008-12-16 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus. Embo J., 27, 2008
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5AAW
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![BU of 5aaw by Molmil](/molmil-images/mine/5aaw) | Structure of a redesigned cross-reactive antibody to dengue virus with increased in vivo potency | Descriptor: | DENGUE SEROTYPE 4 ENVELOPE PROTEIN DOMAIN 3, SCFV513 | Authors: | Wong, Y, Robinson, L, Lescar, J, Sasisekharan, R. | Deposit date: | 2015-07-30 | Release date: | 2015-09-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.27 Å) | Cite: | Structure-Guided Design of an Anti-Dengue Antibody Directed to a Non-Immunodominant Epitope. Cell(Cambridge,Mass.), 162, 2015
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5AAM
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![BU of 5aam by Molmil](/molmil-images/mine/5aam) | Structure of a redesigned cross-reactive antibody to dengue virus with increased in vivo potency | Descriptor: | ENVELOPE PROTEIN, SCFV513 | Authors: | Wong, Y.H, Robinson, L.N, Lescar, J, Sasisekharan, R. | Deposit date: | 2015-07-27 | Release date: | 2015-08-05 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.49 Å) | Cite: | Structure-Guided Design of an Anti-Dengue Antibody Directed to a Non-Immunodominant Epitope. Cell(Cambridge,Mass.), 162, 2015
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7E72
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![BU of 7e72 by Molmil](/molmil-images/mine/7e72) | Crystal structure of Tie2-agonistic antibody in complex with human Tie2 Fn2-3 | Descriptor: | 1,2-ETHANEDIOL, Angiopoietin-1 receptor, the chimeric Fab fragment of 3H7 (heavy chain), ... | Authors: | Kim, H.M, Jo, G.H, Hong, H.J, Han, A. | Deposit date: | 2021-02-25 | Release date: | 2021-11-10 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.094 Å) | Cite: | Structural insights into the clustering and activation of Tie2 receptor mediated by Tie2 agonistic antibody. Nat Commun, 12, 2021
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6K7O
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![BU of 6k7o by Molmil](/molmil-images/mine/6k7o) | Complex structure of LILRB4 and h128-3 antibody | Descriptor: | Leukocyte immunoglobulin-like receptor subfamily B member 4, h128-3 Fab heavy chain, h128-3 Fab light chain | Authors: | Song, H, Chai, Y, Xu, X, Gao, F.G. | Deposit date: | 2019-06-08 | Release date: | 2019-07-03 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (3.004 Å) | Cite: | Disrupting LILRB4/APOE Interaction by an Efficacious Humanized Antibody Reverses T-cell Suppression and Blocks AML Development. Cancer Immunol Res, 7, 2019
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6CA6
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![BU of 6ca6 by Molmil](/molmil-images/mine/6ca6) | |
2CJU
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![BU of 2cju by Molmil](/molmil-images/mine/2cju) | |
2R0L
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![BU of 2r0l by Molmil](/molmil-images/mine/2r0l) | Short Form HGFA with Inhibitory Fab75 | Descriptor: | Hepatocyte growth factor activator, antibody heavy chain, Fab portion only, ... | Authors: | Eigenbrot, C, Shia, S. | Deposit date: | 2007-08-20 | Release date: | 2007-12-25 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural insight into distinct mechanisms of protease inhibition by antibodies. Proc.Natl.Acad.Sci.Usa, 104, 2007
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7D5Q
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![BU of 7d5q by Molmil](/molmil-images/mine/7d5q) | Structure of NorC transporter (K398A mutant) in an outward-open conformation in complex with a single-chain Indian camelid antibody | Descriptor: | Drug transporter, putative, ICab, ... | Authors: | Kumar, S, Athreya, A, Penmatsa, A. | Deposit date: | 2020-09-27 | Release date: | 2021-06-09 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Structural basis of inhibition of a transporter from Staphylococcus aureus, NorC, through a single-domain camelid antibody. Commun Biol, 4, 2021
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7D5P
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![BU of 7d5p by Molmil](/molmil-images/mine/7d5p) | Structure of NorC transporter in an outward-open conformation in complex with a single-chain Indian camelid antibody | Descriptor: | Drug transporter, putative, ICab, ... | Authors: | Kumar, S, Athreya, A, Penmatsa, A. | Deposit date: | 2020-09-27 | Release date: | 2021-06-09 | Last modified: | 2021-07-14 | Method: | X-RAY DIFFRACTION (3.65 Å) | Cite: | Structural basis of inhibition of a transporter from Staphylococcus aureus, NorC, through a single-domain camelid antibody. Commun Biol, 4, 2021
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7RNJ
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![BU of 7rnj by Molmil](/molmil-images/mine/7rnj) | S2P6 Fab fragment bound to the SARS-CoV/SARS-CoV-2 spike stem helix peptide | Descriptor: | Monoclonal antibody S2P6 Fab heavy chain, Monoclonal antibody S2P6 Fab light chain, SULFATE ION, ... | Authors: | Snell, G, Czudnochowski, N, Croll, T.I, Nix, J.C, Corti, D, Cameroni, E, Pinto, D, Beltramello, M, Sauer, M.M, Veesler, D. | Deposit date: | 2021-07-29 | Release date: | 2021-08-11 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | Broad betacoronavirus neutralization by a stem helix-specific human antibody. Science, 373, 2021
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1I9R
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![BU of 1i9r by Molmil](/molmil-images/mine/1i9r) | STRUCTURE OF CD40L IN COMPLEX WITH THE FAB FRAGMENT OF HUMANIZED 5C8 ANTIBODY | Descriptor: | CD40 LIGAND, IMMUNOGLOBULIN H, IMMUNOGLOBULIN L, ... | Authors: | Karpusas, M, Lucci, J, Ferrant, J, Benjamin, C, Hsu, Y.-M. | Deposit date: | 2001-03-20 | Release date: | 2002-03-20 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Structure of CD40 ligand in complex with the Fab fragment of a neutralizing humanized antibody. Structure, 9, 2001
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1QGC
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![BU of 1qgc by Molmil](/molmil-images/mine/1qgc) | |
8EQF
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![BU of 8eqf by Molmil](/molmil-images/mine/8eqf) | cryoEM structure of a broadly neutralizing anti-SARS-CoV-2 antibody STI-9167 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab heavy chain, Fab light chain, ... | Authors: | Bajic, G. | Deposit date: | 2022-10-07 | Release date: | 2023-10-11 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (3.16 Å) | Cite: | An in vitro experimental pipeline to characterize the epitope of a SARS-CoV-2 neutralizing antibody. Mbio, 15, 2024
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4OUU
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![BU of 4ouu by Molmil](/molmil-images/mine/4ouu) | anti-MT1-MMP monoclonal antibody | Descriptor: | anti_MT1-MMP Heavy chain, anti_MT1-MMP light chain | Authors: | Udi, Y, Grossman, M, Solomonov, I, Dym, O, Rozenberg, H, Koziol, A, Cuniasse, P, Dive, V, Arroyo, A.G, Irit, S, Israel Structural Proteomics Center (ISPC) | Deposit date: | 2014-02-19 | Release date: | 2014-12-17 | Last modified: | 2015-01-28 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Inhibition mechanism of membrane metalloprotease by an exosite-swiveling conformational antibody. Structure, 23, 2015
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