1BJ1

VASCULAR ENDOTHELIAL GROWTH FACTOR IN COMPLEX WITH A NEUTRALIZING ANTIBODY

Summary for 1BJ1

• Entry DOI: 10.2210/pdb1bj1/pdb
• Descriptor: Fab fragment, light chain, Fab fragment, heavy chain, Vascular endothelial growth factor A, ... (5 entities in total)
• Functional Keywords: complex (antibody-antigen), angiogenic factor, immune system
• Biological source: Mus musculus (house mouse); More
• Total number of polymer chains: 6
• Total formula weight: 120814.91

Authors

Muller, Y.A.,Christinger, H.W.,De Vos, A.M. (deposition date: 1998-06-30, release date: 1999-01-13, Last modification date: 2023-08-02)

• Primary citation: Muller, Y.A.,Chen, Y.,Christinger, H.W.,Li, B.,Cunningham, B.C.,Lowman, H.B.,de Vos, A.M.; VEGF and the Fab fragment of a humanized neutralizing antibody: crystal structure of the complex at 2.4 A resolution and mutational analysis of the interface.; Structure, 6:1153-1167, 1998; PubMed: 9753694; DOI: 10.1016/S0969-2126(98)00116-6

Experimental method

X-RAY DIFFRACTION (2.4 Å)