1I9R
STRUCTURE OF CD40L IN COMPLEX WITH THE FAB FRAGMENT OF HUMANIZED 5C8 ANTIBODY
Summary for 1I9R
Entry DOI | 10.2210/pdb1i9r/pdb |
Descriptor | CD40 LIGAND, IMMUNOGLOBULIN H, IMMUNOGLOBULIN L, ... (4 entities in total) |
Functional Keywords | beta-sheet sandwich, immunoglobulin, cytokine-immune system complex, cytokine/immune system |
Biological source | Homo sapiens (human) More |
Cellular location | Cell membrane; Single-pass type II membrane protein. CD40 ligand, soluble form: Secreted: P29965 |
Total number of polymer chains | 9 |
Total formula weight | 189191.30 |
Authors | Karpusas, M.,Lucci, J.,Ferrant, J.,Benjamin, C.,Hsu, Y.-M. (deposition date: 2001-03-20, release date: 2002-03-20, Last modification date: 2023-08-09) |
Primary citation | Karpusas, M.,Lucci, J.,Ferrant, J.,Benjamin, C.,Taylor, F.R.,Strauch, K.,Garber, E.,Hsu, Y.M. Structure of CD40 ligand in complex with the Fab fragment of a neutralizing humanized antibody. Structure, 9:321-329, 2001 Cited by PubMed: 11525169DOI: 10.1016/S0969-2126(01)00590-1 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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