5AAW
Structure of a redesigned cross-reactive antibody to dengue virus with increased in vivo potency
Replaces: 4UDZSummary for 5AAW
Entry DOI | 10.2210/pdb5aaw/pdb |
Related | 5AAM |
Descriptor | SCFV513, DENGUE SEROTYPE 4 ENVELOPE PROTEIN DOMAIN 3 (3 entities in total) |
Functional Keywords | viral protein, scfv dengue antibody envelope domain iii |
Biological source | MUS MUSCULUS (HOUSE MOUSE) More |
Total number of polymer chains | 12 |
Total formula weight | 240720.29 |
Authors | Wong, Y.,Robinson, L.,Lescar, J.,Sasisekharan, R. (deposition date: 2015-07-30, release date: 2015-09-30, Last modification date: 2024-01-10) |
Primary citation | Robinson, L.N.,Tharakaraman, K.,Rowley, K.J.,Costa, V.V.,Chan, K.R.,Wong, Y.H.,Ong, L.C.,Tan, H.C.,Koch, T.,Cain, D.,Kirloskar, R.,Viswanathan, K.,Liew, C.W.,Tissire, H.,Ramakrishnan, B.,Myette, J.R.,Babcock, G.J.,Sasisekharan, V.,Alonso, S.,Chen, J.,Lescar, J.,Shriver, Z.,Ooi, E.E.,Sasisekharan, R. Structure-Guided Design of an Anti-Dengue Antibody Directed to a Non-Immunodominant Epitope. Cell(Cambridge,Mass.), 162:493-, 2015 Cited by PubMed: 26189681DOI: 10.1016/J.CELL.2015.06.057 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.27 Å) |
Structure validation
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