3EYF

Crystal structure of anti-human cytomegalovirus antibody 8f9 plus gB peptide

Summary for 3EYF

• Entry DOI: 10.2210/pdb3eyf/pdb
• Related: 3EYO 3EYQ 3F12
• Descriptor: 8f9 Fab, AD-2, Synthetic peptide, ... (5 entities in total)
• Functional Keywords: cytomegalovirus, antibody, immunoglobulin domain, cleavage on pair of basic residues, envelope protein, glycoprotein, host-virus interaction, membrane, transmembrane, virion, immune system
• Biological source: Homo sapiens; More
• Cellular location: Virion membrane ; Single-pass type I membrane protein : P13201
• Total number of polymer chains: 6
• Total formula weight: 101966.14

Authors

Thomson, C.A.,Bryson, S.,McLean, G.R.,Creagh, A.L.,Pai, E.F.,Schrader, J.W. (deposition date: 2008-10-20, release date: 2008-12-16, Last modification date: 2023-09-06)

• Primary citation: Thomson, C.A.,Bryson, S.,McLean, G.R.,Creagh, A.L.,Pai, E.F.,Schrader, J.W.; Germline V-genes sculpt the binding site of a family of antibodies neutralizing human cytomegalovirus.; Embo J., 27:2592-2602, 2008; PubMed: 18772881; DOI: 10.1038/emboj.2008.179

Experimental method

X-RAY DIFFRACTION (2.3 Å)