2AJ3

Crystal Structure of a Cross-Reactive HIV-1 Neutralizing CD4-Binding Site Antibody Fab m18

Summary for 2AJ3

• Entry DOI: 10.2210/pdb2aj3/pdb
• Related: 1HZH 1RHH
• Descriptor: Fab m18, Light Chain, Fab m18, Heavy Chain, SULFATE ION, ... (4 entities in total)
• Functional Keywords: hiv, antibody, fab, cd4-binding, immunoglobulin, immune system
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 143881.33

Authors

Prabakaran, P.,Gan, J.,Wu, Y.Q.,Zhang, M.Y.,Dimitrov, D.S.,Ji, X. (deposition date: 2005-08-01, release date: 2006-03-28, Last modification date: 2023-08-30)

• Primary citation: Prabakaran, P.,Gan, J.,Wu, Y.Q.,Zhang, M.Y.,Dimitrov, D.S.,Ji, X.; Structural mimicry of CD4 by a cross-reactive HIV-1 neutralizing antibody with CDR-H2 and H3 containing unique motifs.; J.Mol.Biol., 357:82-99, 2006; PubMed: 16426633; DOI: 10.1016/j.jmb.2005.12.062

Experimental method

X-RAY DIFFRACTION (2.03 Å)