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6CA6

Crystal structure of PCT64_35S, a broadly neutralizing anti-HIV antibody.

Summary for 6CA6
Entry DOI10.2210/pdb6ca6/pdb
DescriptorPCT64_35S light chain, PCT64_35S heavy chain, DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
Functional Keywordsantibody, neutralizing, immune system
Biological sourceHomo sapiens
More
Total number of polymer chains4
Total formula weight98717.82
Authors
Murrell, S.,Wilson, I.A. (deposition date: 2018-01-29, release date: 2018-06-27, Last modification date: 2023-11-15)
Primary citationRantalainen, K.,Berndsen, Z.T.,Murrell, S.,Cao, L.,Omorodion, O.,Torres, J.L.,Wu, M.,Umotoy, J.,Copps, J.,Poignard, P.,Landais, E.,Paulson, J.C.,Wilson, I.A.,Ward, A.B.
Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design.
Cell Rep, 23:3249-3261, 2018
Cited by
PubMed: 29898396
DOI: 10.1016/j.celrep.2018.05.046
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.43 Å)
Structure validation

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