4ZYN
 
 | | Crystal Structure of Parkin E3 ubiquitin ligase (linker deletion; delta 86-130) | | Descriptor: | E3 ubiquitin-protein ligase parkin, SULFATE ION, ZINC ION | | Authors: | Lilov, A, Sauve, V, Trempe, J.F, Rodionov, D, Wang, J, Gehring, K. | | Deposit date: | 2015-05-21 | | Release date: | 2015-08-19 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.54 Å) | | Cite: | A Ubl/ubiquitin switch in the activation of Parkin.
Embo J., 34, 2015
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2HTH
 | | Structural basis for ubiquitin recognition by the human EAP45/ESCRT-II GLUE domain | | Descriptor: | Ubiquitin, Vacuolar protein sorting protein 36 | | Authors: | Alam, S.L, Whitby, F.G, Hill, C.P, Sundquist, W.I. | | Deposit date: | 2006-07-25 | | Release date: | 2006-10-24 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain.
Nat.Struct.Mol.Biol., 13, 2006
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2IBI
 | | Covalent Ubiquitin-USP2 Complex | | Descriptor: | ETHANAMINE, Ubiquitin, Ubiquitin carboxyl-terminal hydrolase 2, ... | | Authors: | Walker, J.R, Avvakumov, G.V, Bernstein, G, Xue, S, Finerty Jr, P.J, MacKenzie, F, Weigelt, J, Sundstrom, M, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | | Deposit date: | 2006-09-11 | | Release date: | 2006-10-24 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Covalent Ubiquitin-USP2 Complex
To be Published
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6DC6
 | | Crystal structure of human ubiquitin activating enzyme E1 (Uba1) in complex with ubiquitin | | Descriptor: | MAGNESIUM ION, PYROPHOSPHATE 2-, Ubiquitin, ... | | Authors: | Lv, Z, Yuan, L, Williams, K.M, Atkison, J.H, Olsen, S.K. | | Deposit date: | 2018-05-04 | | Release date: | 2018-10-10 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (3.14 Å) | | Cite: | Crystal structure of a human ubiquitin E1-ubiquitin complex reveals conserved functional elements essential for activity.
J. Biol. Chem., 293, 2018
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4II3
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4IUM
 | | Equine arteritis virus papain-like protease 2 (PLP2) covalently bound to ubiquitin | | Descriptor: | GLYCEROL, Ubiquitin, ZINC ION, ... | | Authors: | Bailey-Elkin, B.A, James, T.W, Mark, B.L. | | Deposit date: | 2013-01-21 | | Release date: | 2013-02-13 | | Last modified: | 2013-03-20 | | Method: | X-RAY DIFFRACTION (1.45 Å) | | Cite: | Deubiquitinase function of arterivirus papain-like protease 2 suppresses the innate immune response in infected host cells.
Proc.Natl.Acad.Sci.USA, 110, 2013
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4JQW
 | | Crystal Structure of a Complex of NOD1 CARD and Ubiquitin | | Descriptor: | Nucleotide-binding oligomerization domain-containing protein 1, PHOSPHATE ION, Polyubiquitin-C | | Authors: | Ver Heul, A.M, Gakhar, L, Piper, R.C, Ramaswamy, S. | | Deposit date: | 2013-03-20 | | Release date: | 2014-03-26 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Crystal structure of a complex of NOD1 CARD and ubiquitin
Plos One, 9, 2014
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4KSK
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4JIO
 | | Bro1 V domain and ubiquitin | | Descriptor: | BRO1, Ubiquitin | | Authors: | Pashkova, N, Gakhar, L, Piper, R.C. | | Deposit date: | 2013-03-06 | | Release date: | 2013-06-19 | | Last modified: | 2013-07-10 | | Method: | X-RAY DIFFRACTION (3.6 Å) | | Cite: | The yeast alix homolog bro1 functions as a ubiquitin receptor for protein sorting into multivesicular endosomes.
Dev.Cell, 25, 2013
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6DGF
 | | Ubiquitin Variant bound to USP2 | | Descriptor: | Polyubiquitin-B, SULFATE ION, Ubiquitin carboxyl-terminal hydrolase 2, ... | | Authors: | Manczyk, N, Sicheri, F. | | Deposit date: | 2018-05-17 | | Release date: | 2019-02-13 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.34 Å) | | Cite: | Yeast Two-Hybrid Analysis for Ubiquitin Variant Inhibitors of Human Deubiquitinases.
J. Mol. Biol., 431, 2019
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3PLV
 | | Structure of Hub-1 protein in complex with Snu66 peptide (HINDII) | | Descriptor: | 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, Ubiquitin-like modifier HUB1 | | Authors: | Mishra, S.K, Ammon, T, Popowicz, G.M, Krajewski, M, Nagel, R.J, Ares, M, Holak, T.A, Jentsch, S. | | Deposit date: | 2010-11-15 | | Release date: | 2011-06-01 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Role of the ubiquitin-like protein Hub1 in splice-site usage and alternative splicing.
Nature, 474, 2011
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3PRM
 | | Structural analysis of a viral OTU domain protease from the Crimean-Congo Hemorrhagic Fever virus in complex with human ubiquitin | | Descriptor: | Polyubiquitin-B (Fragment), RNA-directed RNA polymerase L | | Authors: | Capodagli, G.C, McKercher, M.A, Baker, E.A, Masters, E.M, Brunzelle, J.S, Pegan, S.D. | | Deposit date: | 2010-11-30 | | Release date: | 2011-01-26 | | Last modified: | 2023-02-22 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural analysis of a viral ovarian tumor domain protease from the crimean-congo hemorrhagic Fever virus in complex with covalently bonded ubiquitin.
J.Virol., 85, 2011
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3Q3F
 | | Engineering Domain-Swapped Binding Interfaces by Mutually Exclusive Folding: Insertion of Ubiquitin into position 103 of Barnase | | Descriptor: | Ribonuclease/Ubiquitin chimeric protein, SULFATE ION | | Authors: | Ha, J.-H, Karchin, J.M, Walker-Kopp, N, Huang, L.-S, Berry, E.A, Loh, S.N. | | Deposit date: | 2010-12-21 | | Release date: | 2012-01-25 | | Last modified: | 2023-09-13 | | Method: | X-RAY DIFFRACTION (2.169 Å) | | Cite: | Engineering domain-swapped binding interfaces by mutually exclusive folding.
J.Mol.Biol., 416, 2012
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3PHW
 | | OTU Domain of Crimean Congo Hemorrhagic Fever Virus in complex with Ubiquitin | | Descriptor: | ETHANAMINE, RNA-directed RNA polymerase L, Ubiquitin-40S ribosomal protein S27a | | Authors: | Akutsu, M, Ye, Y, Virdee, S, Komander, D. | | Deposit date: | 2010-11-04 | | Release date: | 2011-02-02 | | Last modified: | 2014-08-06 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | Molecular basis for ubiquitin and ISG15 cross-reactivity in viral ovarian tumor domains.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3PSE
 | | Structure of a viral OTU domain protease bound to interferon-stimulated gene 15 (ISG15) | | Descriptor: | 1.7.6 3-bromanylpropan-1-amine, GLYCEROL, RNA polymerase, ... | | Authors: | Bacik, J.P, James, T.W, Frias-Staheli, N, Garcia-Sastre, A, Mark, B.L. | | Deposit date: | 2010-12-01 | | Release date: | 2011-01-19 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3PT2
 | | Structure of a viral OTU domain protease bound to Ubiquitin | | Descriptor: | 1.7.6 3-bromanylpropan-1-amine, ACETATE ION, RNA polymerase, ... | | Authors: | James, T.W, Bacik, J.P, Frias-Staheli, N, Garcia-Sastre, A, Mark, B.L. | | Deposit date: | 2010-12-02 | | Release date: | 2011-01-19 | | Last modified: | 2023-05-31 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease.
Proc.Natl.Acad.Sci.USA, 108, 2011
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4KSL
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4K95
 | | Crystal Structure of Parkin | | Descriptor: | E3 ubiquitin-protein ligase parkin, ZINC ION | | Authors: | Seirafi, M, Menade, M, Sauve, V, Kozlov, G, Trempe, J.-F, Nagar, B, Gehring, K. | | Deposit date: | 2013-04-19 | | Release date: | 2013-05-15 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (6.499 Å) | | Cite: | Structure of parkin reveals mechanisms for ubiquitin ligase activation.
Science, 340, 2013
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4LJO
 | | Structure of an active ligase (HOIP)/ubiquitin transfer complex | | Descriptor: | E3 ubiquitin-protein ligase RNF31, IMIDAZOLE, Polyubiquitin-C, ... | | Authors: | Rana, R.R, Stieglitz, B, Koliopoulos, M.G, Morris-Davies, A.C, Christodoulou, E, Howell, S, Brown, N.R, Rittinger, K. | | Deposit date: | 2013-07-05 | | Release date: | 2013-10-16 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.564 Å) | | Cite: | Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP.
Nature, 503, 2013
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4I6L
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6FGE
 | | Crystal structure of human ZUFSP/ZUP1 in complex with ubiquitin | | Descriptor: | ACETATE ION, AMMONIUM ION, DI(HYDROXYETHYL)ETHER, ... | | Authors: | Kwasna, D, Abdul Rehman, S.A, Kulathu, Y. | | Deposit date: | 2018-01-10 | | Release date: | 2018-04-04 | | Last modified: | 2018-04-18 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.
Mol. Cell, 70, 2018
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4LCD
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3PLU
 | | Structure of Hub-1 protein in complex with Snu66 peptide (HINDI) | | Descriptor: | 66 kDa U4/U6.U5 small nuclear ribonucleoprotein component, Ubiquitin-like modifier HUB1 | | Authors: | Mishra, S.K, Ammon, T, Popowicz, G.M, Krajewski, M, Nagel, R.J, Ares, M, Holak, T.A, Jentsch, S. | | Deposit date: | 2010-11-15 | | Release date: | 2011-06-01 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Role of the ubiquitin-like protein Hub1 in splice-site usage and alternative splicing.
Nature, 474, 2011
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6EI1
 | | Crystal structure of the covalent complex between deubiquitinase ZUFSP (ZUP1) and Ubiquitin-PA | | Descriptor: | GLYCEROL, MALONATE ION, Polyubiquitin-B, ... | | Authors: | Pichlo, C, Baumann, U, Hofmann, K, Hermanns, T. | | Deposit date: | 2017-09-16 | | Release date: | 2018-03-07 | | Last modified: | 2019-10-16 | | Method: | X-RAY DIFFRACTION (1.732 Å) | | Cite: | A family of unconventional deubiquitinases with modular chain specificity determinants.
Nat Commun, 9, 2018
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3OLM
 | | Structure and Function of a Ubiquitin Binding Site within the Catalytic Domain of a HECT Ubiquitin Ligase | | Descriptor: | E3 ubiquitin-protein ligase RSP5, Ubiquitin | | Authors: | Kim, H.C, Steffen, A, Chen, J, Huibregtse, J.M. | | Deposit date: | 2010-08-26 | | Release date: | 2011-03-23 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.495 Å) | | Cite: | Structure and function of a HECT domain ubiquitin-binding site.
Embo Rep., 12, 2011
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