7O2W

Structure of the C9orf72-SMCR8 complex

Summary for 7O2W

• Entry DOI: 10.2210/pdb7o2w/pdb
• EMDB information: 12700
• Descriptor: Ubiquitin-like protein SMT3,Guanine nucleotide exchange C9orf72, Guanine nucleotide exchange protein SMCR8,Guanine nucleotide exchange protein SMCR8,Maltose/maltodextrin-binding periplasmic protein (2 entities in total)
• Functional Keywords: denn domain, coiled-coil, gtpase-activating protein, protein binding
• Biological source: Saccharomyces cerevisiae S288c (Baker's yeast); More
• Total number of polymer chains: 2
• Total formula weight: 201557.13

Authors

Noerpel, J.,Cavadini, S.,Schenk, A.D.,Graff-Meyer, A.,Chao, J.,Bhaskar, V. (deposition date: 2021-03-31, release date: 2021-07-21, Last modification date: 2022-02-02)

• Primary citation: Norpel, J.,Cavadini, S.,Schenk, A.D.,Graff-Meyer, A.,Hess, D.,Seebacher, J.,Chao, J.A.,Bhaskar, V.; Structure of the human C9orf72-SMCR8 complex reveals a multivalent protein interaction architecture.; Plos Biol., 19:e3001344-e3001344, 2021; PubMed: 34297726; DOI: 10.1371/journal.pbio.3001344

Experimental method

ELECTRON MICROSCOPY