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7O2W

Structure of the C9orf72-SMCR8 complex

Functional Information from GO Data
ChainGOidnamespacecontents
A0000794cellular_componentcondensed nuclear chromosome
A0000932cellular_componentP-body
A0001933biological_processnegative regulation of protein phosphorylation
A0005085molecular_functionguanyl-nucleotide exchange factor activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005634cellular_componentnucleus
A0005737cellular_componentcytoplasm
A0005764cellular_componentlysosome
A0005768cellular_componentendosome
A0005776cellular_componentautophagosome
A0005829cellular_componentcytosol
A0005940cellular_componentseptin ring
A0006897biological_processendocytosis
A0006914biological_processautophagy
A0010494cellular_componentcytoplasmic stress granule
A0010506biological_processregulation of autophagy
A0016020cellular_componentmembrane
A0016239biological_processpositive regulation of macroautophagy
A0016925biological_processprotein sumoylation
A0030424cellular_componentaxon
A0030425cellular_componentdendrite
A0030426cellular_componentgrowth cone
A0031267molecular_functionsmall GTPase binding
A0031386molecular_functionprotein tag activity
A0031965cellular_componentnuclear membrane
A0032045cellular_componentguanyl-nucleotide exchange factor complex
A0032880biological_processregulation of protein localization
A0034063biological_processstress granule assembly
A0042802molecular_functionidentical protein binding
A0042995cellular_componentcell projection
A0043005cellular_componentneuron projection
A0043204cellular_componentperikaryon
A0043231cellular_componentintracellular membrane-bounded organelle
A0043547biological_processpositive regulation of GTPase activity
A0044295cellular_componentaxonal growth cone
A0044304cellular_componentmain axon
A0044389molecular_functionubiquitin-like protein ligase binding
A0045202cellular_componentsynapse
A0048675biological_processaxon extension
A0090543cellular_componentFlemming body
A0098793cellular_componentpresynapse
A0098794cellular_componentpostsynapse
A0099523cellular_componentpresynaptic cytosol
A0110053biological_processregulation of actin filament organization
A1902774biological_processlate endosome to lysosome transport
A1903432biological_processregulation of TORC1 signaling
A1990316cellular_componentAtg1/ULK1 kinase complex
A2000785biological_processregulation of autophagosome assembly
B0005096molecular_functionGTPase activator activity
B0005515molecular_functionprotein binding
B0006974biological_processDNA damage response
B0008643biological_processcarbohydrate transport
B0015768biological_processmaltose transport
B0016020cellular_componentmembrane
B0030288cellular_componentouter membrane-bounded periplasmic space
B0034219biological_processcarbohydrate transmembrane transport
B0034289biological_processdetection of maltose stimulus
B0042597cellular_componentperiplasmic space
B0042956biological_processmaltodextrin transmembrane transport
B0043190cellular_componentATP-binding cassette (ABC) transporter complex
B0055052cellular_componentATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
B0055085biological_processtransmembrane transport
B0060326biological_processcell chemotaxis
B1901982molecular_functionmaltose binding
B1990060cellular_componentmaltose transport complex
Functional Information from PROSITE/UniProt
site_idPS01037
Number of Residues18
DetailsSBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN
ChainResidueDetails
BPRO1062-ASN1079

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Phosphoserine; by TBK1 => ECO:0000269|PubMed:27103069
ChainResidueDetails
BSER402

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163
ChainResidueDetails
BSER417
BSER790

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: Phosphothreonine; by TBK1 => ECO:0000269|PubMed:27103069
ChainResidueDetails
BTHR796

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PDB entries from 2024-07-17

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