4LJO

Structure of an active ligase (HOIP)/ubiquitin transfer complex

Summary for 4LJO

Related4LJP 4LJQ
DescriptorE3 ubiquitin-protein ligase RNF31, Polyubiquitin-C, ZINC ION, ... (5 entities in total)
Functional Keywordse3 ligase-ubiquitin complex, ligase, hoip, rnf31, ubiquitin, rbr ligase, e3 ligase, ring domain, ibr domain, zinc finger
Biological sourceHomo sapiens (human)
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Total number of polymer chains2
Total molecular weight34072.62
Authors
Rana, R.R.,Stieglitz, B.,Koliopoulos, M.G.,Morris-Davies, A.C.,Christodoulou, E.,Howell, S.,Brown, N.R.,Rittinger, K. (deposition date: 2013-07-05, release date: 2013-10-16, Last modification date: 2019-07-17)
Primary citation
Stieglitz, B.,Rana, R.R.,Koliopoulos, M.G.,Morris-Davies, A.C.,Schaeffer, V.,Christodoulou, E.,Howell, S.,Brown, N.R.,Dikic, I.,Rittinger, K.
Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP.
Nature, 503:422-426, 2013
PubMed: 24141947 (PDB entries with the same primary citation)
DOI: 10.1038/nature12638
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.564 Å)
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.21430 2.0% 7.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report