Structure of an active ligase (HOIP)/ubiquitin transfer complex

Summary for 4LJO

Related4LJP 4LJQ
DescriptorE3 ubiquitin-protein ligase RNF31, Polyubiquitin-C, ZINC ION, ... (5 entities in total)
Functional Keywordse3 ligase-ubiquitin complex, ligase, hoip, rnf31, ubiquitin, rbr ligase, e3 ligase, ring domain, ibr domain, zinc finger
Biological sourceHomo sapiens (human)
Total number of polymer chains2
Total molecular weight34072.62
Rana, R.R.,Stieglitz, B.,Koliopoulos, M.G.,Morris-Davies, A.C.,Christodoulou, E.,Howell, S.,Brown, N.R.,Rittinger, K. (deposition date: 2013-07-05, release date: 2013-10-16, Last modification date: 2019-07-17)
Primary citation
Stieglitz, B.,Rana, R.R.,Koliopoulos, M.G.,Morris-Davies, A.C.,Schaeffer, V.,Christodoulou, E.,Howell, S.,Brown, N.R.,Dikic, I.,Rittinger, K.
Structural basis for ligase-specific conjugation of linear ubiquitin chains by HOIP.
Nature, 503:422-426, 2013
PubMed: 24141947 (PDB entries with the same primary citation)
DOI: 10.1038/nature12638
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers 0.21430 2.0% 7.9%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report