4K95

Crystal Structure of Parkin

Summary for 4K95

• Entry DOI: 10.2210/pdb4k95/pdb
• Related: 4K7D
• Descriptor: E3 ubiquitin-protein ligase parkin, ZINC ION (2 entities in total)
• Functional Keywords: ubiquitin-like domain, ring domains, zinc fingers, rbr ubiquitin ligase, zinc finger, ubch7, ubiquitin, mitochondria, ligase
• Biological source: Rattus norvegicus (brown rat,rat,rats)
• Cellular location: Nucleus (By similarity): Q9JK66
• Total number of polymer chains: 12
• Total formula weight: 632140.62

Authors

Seirafi, M.,Menade, M.,Sauve, V.,Kozlov, G.,Trempe, J.-F.,Nagar, B.,Gehring, K. (deposition date: 2013-04-19, release date: 2013-05-15, Last modification date: 2023-09-20)

• Primary citation: Trempe, J.F.,Sauve, V.,Grenier, K.,Seirafi, M.,Tang, M.Y.,Menade, M.,Al-Abdul-Wahid, S.,Krett, J.,Wong, K.,Kozlov, G.,Nagar, B.,Fon, E.A.,Gehring, K.; Structure of parkin reveals mechanisms for ubiquitin ligase activation.; Science, 340:1451-1455, 2013; PubMed: 23661642; DOI: 10.1126/science.1237908

Experimental method

X-RAY DIFFRACTION (6.499 Å)