3SDL

Crystal structure of human ISG15 in complex with NS1 N-terminal region from influenza B virus, Northeast Structural Genomics Consortium Target IDs HX6481, HR2873, and OR2

Summary for 3SDL

Entry DOI	10.2210/pdb3sdl/pdb
Related	1XEQ 1Z2M
Descriptor	Non-structural protein 1, Ubiquitin-like protein ISG15 (3 entities in total)
Functional Keywords	structural genomics, psi-biology, northeast structural genomics consortium, nesg, protein complex, viral protein/antiviral protein, viral protein-antiviral protein complex
Biological source	Influenza B virus More
Cellular location	Host cytoplasm : P03502 Cytoplasm : P05161
Total number of polymer chains	4
Total formula weight	62407.30
Authors	Guan, R.,Ma, L.-C.,Krug, R.M.,Montelione, G.T.,Northeast Structural Genomics Consortium (NESG) (deposition date: 2011-06-09, release date: 2011-07-20, Last modification date: 2023-11-29)
Primary citation	Guan, R.,Ma, L.C.,Leonard, P.G.,Amer, B.R.,Sridharan, H.,Zhao, C.,Krug, R.M.,Montelione, G.T. Structural basis for the sequence-specific recognition of human ISG15 by the NS1 protein of influenza B virus. Proc.Natl.Acad.Sci.USA, 108:13468-13473, 2011 Cited by PubMed: 21808041 DOI: 10.1073/pnas.1107032108 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.29 Å)

Structure validation