3SDL

Crystal structure of human ISG15 in complex with NS1 N-terminal region from influenza B virus, Northeast Structural Genomics Consortium Target IDs HX6481, HR2873, and OR2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Non-structural protein 1	polymer	113	13124.0	2	UniProt (P03502) Pfam (PF02942)	Influenza B virus	NS1, NS1B
2	C, D (C, D)	Ubiquitin-like protein ISG15	polymer	164	18079.7	2	UniProt (P05161) Pfam (PF00240)	Homo sapiens (human)	Interferon-induced 15 kDa protein, Interferon-induced 17 kDa protein, IP17, Ubiquitin cross-reactive protein, hUCRP
3	E, F, G, H (A, B, C, D)	water	water		18.0	142	Chemie (HOH)

Sequence modifications

A, B: 1 - 103 (UniProt: P03502)

PDB	External Database	Details
Met -9	-	expression tag
Gly -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

C, D: 1 - 157 (UniProt: P05161)

PDB	External Database	Details
Ser -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
His -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	62407.3
All*	Total formula weight	62407.3

*Water molecules are not included.