7RUP
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![BU of 7rup by Molmil](/molmil-images/mine/7rup) | Structure of the human GIGYF2-TNRC6A complex | Descriptor: | GRB10-interacting GYF protein 2, SULFATE ION, Trinucleotide repeat-containing gene 6A protein | Authors: | Sobti, M, Mead, B.J, Igreja, C, Stewart, A.G, Christie, M. | Deposit date: | 2021-08-18 | Release date: | 2022-08-24 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.23 Å) | Cite: | Molecular basis for GIGYF-TNRC6 complex assembly. Rna, 29, 2023
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4MGN
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![BU of 4mgn by Molmil](/molmil-images/mine/4mgn) | |
6SVS
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![BU of 6svs by Molmil](/molmil-images/mine/6svs) | Crystal Structure of U:A-U-rich RNA triple helix with 11 consecutive base triples | Descriptor: | ADENOSINE-5'-PHOSPHATE-2',3'-CYCLIC PHOSPHATE, CALCIUM ION, GLYCEROL, ... | Authors: | Ruszkowska, A, Ruszkowski, M, Hulewicz, J.P, Dauter, Z, Brown, J.A. | Deposit date: | 2019-09-18 | Release date: | 2020-01-01 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Molecular structure of a U•A-U-rich RNA triple helix with 11 consecutive base triples. Nucleic Acids Res., 48, 2020
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4MGM
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![BU of 4mgm by Molmil](/molmil-images/mine/4mgm) | |
7WM4
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![BU of 7wm4 by Molmil](/molmil-images/mine/7wm4) | Cryo-EM structure of tetrameric TLR3 in complex with dsRNA (90 bp) | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RNA (81-MER), ... | Authors: | Sakaniwa, K, Ohto, U, Shimizu, T. | Deposit date: | 2022-01-14 | Release date: | 2023-01-25 | Last modified: | 2023-08-30 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | TLR3 forms a laterally aligned multimeric complex along double-stranded RNA for efficient signal transduction. Nat Commun, 14, 2023
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1FT8
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![BU of 1ft8 by Molmil](/molmil-images/mine/1ft8) | |
3OVS
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![BU of 3ovs by Molmil](/molmil-images/mine/3ovs) | How the CCA-adding Enzyme Selects Adenine over Cytosine in Position 76 of tRNA | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, CCA-Adding Enzyme, ... | Authors: | Pan, B.C, Xiong, Y, Steitz, T.A. | Deposit date: | 2010-09-17 | Release date: | 2010-12-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | How the CCA-Adding Enzyme Selects Adenine over Cytosine at Position 76 of tRNA. Science, 330, 2010
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3OVB
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![BU of 3ovb by Molmil](/molmil-images/mine/3ovb) | How the CCA-adding Enzyme Selects Adenine over Cytosine in Position 76 of tRNA | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, CCA-Adding Enzyme, ... | Authors: | Pan, B.C, Xiong, Y, Steitz, T.A. | Deposit date: | 2010-09-16 | Release date: | 2010-12-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | How the CCA-Adding Enzyme Selects Adenine over Cytosine at Position 76 of tRNA. Science, 330, 2010
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3OUY
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![BU of 3ouy by Molmil](/molmil-images/mine/3ouy) | How the CCA-adding Enzyme Selects Adenine Over Cytosine at Position 76 of tRNA | Descriptor: | 1,2-ETHANEDIOL, CCA-Adding Enzyme, PYROPHOSPHATE 2-, ... | Authors: | Pan, B.C, Xiong, Y, Steitz, T.A. | Deposit date: | 2010-09-15 | Release date: | 2010-12-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.69 Å) | Cite: | How the CCA-Adding Enzyme Selects Adenine over Cytosine at Position 76 of tRNA. Science, 330, 2010
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3OV7
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![BU of 3ov7 by Molmil](/molmil-images/mine/3ov7) | How the CCA-Adding Enzyme Selects Adenine over Cytosine in Position 76 of tRNA | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, CCA-Adding Enzyme, ... | Authors: | Pan, B.C, Xiong, Y, Steitz, T.A. | Deposit date: | 2010-09-15 | Release date: | 2010-12-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | How the CCA-Adding Enzyme Selects Adenine over Cytosine at Position 76 of tRNA. Science, 330, 2010
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3OVA
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![BU of 3ova by Molmil](/molmil-images/mine/3ova) | How the CCA-adding Enzyme Selects Adenine over Cytosine in Position 76 of tRNA | Descriptor: | 1,2-ETHANEDIOL, CCA-adding enzyme, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, ... | Authors: | Pan, B.C, Xiong, Y, Steitz, T.A. | Deposit date: | 2010-09-16 | Release date: | 2010-12-01 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | How the CCA-Adding Enzyme Selects Adenine over Cytosine at Position 76 of tRNA. Science, 330, 2010
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4O53
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![BU of 4o53 by Molmil](/molmil-images/mine/4o53) | Crystal Structure of Trichomonas vaginalis Triosephosphate Isomerase Ile45-Leu mutant (Tvag_497370) | Descriptor: | SODIUM ION, Triosephosphate isomerase | Authors: | Lara-Gonzalez, S, Montero-Moran, G.M, Estrella-Hernandez, P, Benitez-Cardoza, C.G, Brieba, L.G. | Deposit date: | 2013-12-19 | Release date: | 2014-12-24 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Engineering mutants with altered dimer-monomer equilibrium reveal the existence of stable monomeric Triosephosphate isomerases To be Published
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4O57
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![BU of 4o57 by Molmil](/molmil-images/mine/4o57) | Crystal Structure of Trichomonas vaginalis Triosephosphate Isomerase Ile45-Tyr mutant (Tvag_497370) | Descriptor: | SODIUM ION, Triosephosphate isomerase | Authors: | Lara-Gonzalez, S, Estrella-Hernandez, P, Montero-Moran, G.M, Benitez-Cardoza, C.G, Brieba, L.G. | Deposit date: | 2013-12-19 | Release date: | 2014-12-24 | Method: | X-RAY DIFFRACTION (1.793 Å) | Cite: | Engineering mutants with altered dimer-monomer equilibrium reveal the existence of stable monomeric Triosephosphate isomerases To be Published
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7OX9
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![BU of 7ox9 by Molmil](/molmil-images/mine/7ox9) | Target-bound SpCas9 complex with AAVS1 all-RNA guide | Descriptor: | AAVS1 non-target DNA strand, AAVS1 target DNA strand, CRISPR-associated endonuclease Cas9/Csn1, ... | Authors: | Pacesa, M, Donohoue, P, May, A.P, Jinek, M, Cameron, P. | Deposit date: | 2021-06-22 | Release date: | 2021-09-15 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Conformational control of Cas9 by CRISPR hybrid RNA-DNA guides mitigates off-target activity in T cells. Mol.Cell, 81, 2021
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3VAL
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![BU of 3val by Molmil](/molmil-images/mine/3val) | Structure of U2AF65 variant with BrU5C1 DNA | Descriptor: | 1,4-DIETHYLENE DIOXIDE, DNA (5'-D(*C*UP*UP*UP*(BRU)P*UP*U)-3'), SULFATE ION, ... | Authors: | Jenkins, J.L, Frato, K.H, Kielkopf, C.L. | Deposit date: | 2011-12-29 | Release date: | 2013-02-13 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | U2AF65 adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs. Nucleic Acids Res., 41, 2013
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7ZYH
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![BU of 7zyh by Molmil](/molmil-images/mine/7zyh) | Crystal structure of human CPSF30 in complex with hFip1 | Descriptor: | Cleavage and polyadenylation specificity factor subunit 4, Isoform 4 of Pre-mRNA 3'-end-processing factor FIP1, ZINC ION | Authors: | Muckenfuss, L.M, Jinek, M, Migenda Herranz, A.C, Clerici, M. | Deposit date: | 2022-05-24 | Release date: | 2022-09-14 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Fip1 is a multivalent interaction scaffold for processing factors in human mRNA 3' end biogenesis. Elife, 11, 2022
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7NTN
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![BU of 7ntn by Molmil](/molmil-images/mine/7ntn) | The structure of RRM domain of human TRMT2A at 2 A resolution | Descriptor: | CHLORIDE ION, SODIUM ION, SULFATE ION, ... | Authors: | Davydova, E, Janowski, R, Witzenberger, M, Niessing, D. | Deposit date: | 2021-03-10 | Release date: | 2022-01-19 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (2.016 Å) | Cite: | Small-molecule modulators of TRMT2A decrease PolyQ aggregation and PolyQ-induced cell death. Comput Struct Biotechnol J, 20, 2022
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7NTO
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![BU of 7nto by Molmil](/molmil-images/mine/7nto) | The structure of RRM domain of human TRMT2A at 1.23 A resolution | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, SODIUM ION, ... | Authors: | Witzenberger, M, Janowski, R, Davydova, E, Niessing, D. | Deposit date: | 2021-03-10 | Release date: | 2022-01-19 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.23 Å) | Cite: | Small-molecule modulators of TRMT2A decrease PolyQ aggregation and PolyQ-induced cell death. Comput Struct Biotechnol J, 20, 2022
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4JRI
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![BU of 4jri by Molmil](/molmil-images/mine/4jri) | |
4JUV
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![BU of 4juv by Molmil](/molmil-images/mine/4juv) | |
4JLI
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![BU of 4jli by Molmil](/molmil-images/mine/4jli) | |
6WRN
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![BU of 6wrn by Molmil](/molmil-images/mine/6wrn) | Crystal structure of Mj 3-nitro-tyrosine tRNA synthetase (5B) C70A variant bound to 3-nitro-tyrosine | Descriptor: | META-NITRO-TYROSINE, SODIUM ION, Tyrosine--tRNA ligase | Authors: | Beyer, J.N, Hosseinzadeh, P, Karplus, P.A, Mehl, R.A, Cooley, R.B. | Deposit date: | 2020-04-29 | Release date: | 2020-07-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Overcoming Near-Cognate Suppression in a Release Factor 1-Deficient Host with an Improved Nitro-Tyrosine tRNA Synthetase. J.Mol.Biol., 432, 2020
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4V36
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![BU of 4v36 by Molmil](/molmil-images/mine/4v36) | The structure of L-PGS from Bacillus licheniformis | Descriptor: | 2,6-DIAMINO-HEXANOIC ACID AMIDE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, LYSYL-TRNA-DEPENDENT L-YSYL-PHOSPHATIDYLGYCEROL SYNTHASE | Authors: | Krausze, J, Hebecker, S, Heinz, D.W, Moser, J. | Deposit date: | 2014-10-16 | Release date: | 2015-08-19 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structures of Two Bacterial Resistance Factors Mediating tRNA-Dependent Aminoacylation of Phosphatidylglycerol with Lysine or Alanine. Proc.Natl.Acad.Sci.USA, 112, 2015
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6WRQ
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![BU of 6wrq by Molmil](/molmil-images/mine/6wrq) | Crystal structure of Mj 3-nitro-tyrosine tRNA synthetase (5B) S158C variant bound to 3-nitro-tyrosine | Descriptor: | GLYCEROL, META-NITRO-TYROSINE, SODIUM ION, ... | Authors: | Beyer, J.N, Hosseinzadeh, P, Karplus, P.A, Mehl, R.A, Cooley, R.B. | Deposit date: | 2020-04-29 | Release date: | 2020-07-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Overcoming Near-Cognate Suppression in a Release Factor 1-Deficient Host with an Improved Nitro-Tyrosine tRNA Synthetase. J.Mol.Biol., 432, 2020
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6WRT
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![BU of 6wrt by Molmil](/molmil-images/mine/6wrt) | Crystal structure of Mj 3-nitro-tyrosine tRNA synthetase (5B) C70A/S158C variant bound to 3-nitro-tyrosine | Descriptor: | META-NITRO-TYROSINE, SODIUM ION, Tyrosine--tRNA ligase | Authors: | Beyer, J.N, Hosseinzadeh, P, Karplus, P.A, Mehl, R.A, Cooley, R.B. | Deposit date: | 2020-04-30 | Release date: | 2020-07-01 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Overcoming Near-Cognate Suppression in a Release Factor 1-Deficient Host with an Improved Nitro-Tyrosine tRNA Synthetase. J.Mol.Biol., 432, 2020
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