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6HAK

Crystal structure of HIV-1 reverse transcriptase (RT) in complex with a double stranded RNA represents the RT transcription initiation complex prior to nucleotide incorporation

Summary for 6HAK
Entry DOI10.2210/pdb6hak/pdb
Related PRD IDPRD_900003
DescriptorGag-Pol polyprotein, RNA (5'-R(P*AP*GP*UP*GP*GP*CP*GP*GP*CP*CP*GP*AP*AP*CP*AP*GP*GP*GP*AP*C)-3'), RNA (5'-R(P*UP*CP*CP*CP*UP*GP*UP*UP*CP*GP*GP*CP*CP*GP*CP*CP*A)-3'), ... (7 entities in total)
Functional Keywordstrna-lys3, protein-rna cross-link, transcription initiation, viral rna, dna polymerase, transcription
Biological sourceHuman immunodeficiency virus type 1 BH10
More
Total number of polymer chains8
Total formula weight257970.25
Authors
Das, K.,Martinez, S.E.,Arnold, E. (deposition date: 2018-08-07, release date: 2019-04-03, Last modification date: 2024-01-17)
Primary citationDas, K.,Martinez, S.E.,DeStefano, J.J.,Arnold, E.
Structure of HIV-1 RT/dsRNA initiation complex prior to nucleotide incorporation.
Proc.Natl.Acad.Sci.USA, 116:7308-7313, 2019
Cited by
PubMed: 30902895
DOI: 10.1073/pnas.1814170116
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.95 Å)
Structure validation

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