7V6C

Structure of the Dicer-2-R2D2 heterodimer bound to small RNA duplex

Summary for 7V6C

• Entry DOI: 10.2210/pdb7v6c/pdb
• Related: 7V6B
• EMDB information: 31742
• Descriptor: Dicer-2, isoform A, R2D2, RNA (5'-R(P*UP*GP*AP*GP*G)-3'), ... (6 entities in total)
• Functional Keywords: rna binding protein, ribonuclease, double-stranded rna-binding protein
• Biological source: Drosophila melanogaster (Fruit fly); More
• Total number of polymer chains: 6
• Total formula weight: 266517.63

Authors

Yamaguchi, S.,Nishizawa, T.,Kusakizako, T.,Yamashita, K.,Tomita, A.,Hirano, H.,Nishimasu, H.,Nureki, O. (deposition date: 2021-08-20, release date: 2022-03-23, Last modification date: 2022-07-27)

• Primary citation: Yamaguchi, S.,Naganuma, M.,Nishizawa, T.,Kusakizako, T.,Tomari, Y.,Nishimasu, H.,Nureki, O.; Structure of the Dicer-2-R2D2 heterodimer bound to a small RNA duplex.; Nature, 607:393-398, 2022; PubMed: 35768503; DOI: 10.1038/s41586-022-04790-2

Experimental method

ELECTRON MICROSCOPY (3.3 Å)