7DD3

Cryo-EM structure of the pre-mRNA-loaded DEAH-box ATPase/helicase Prp2 in complex with Spp2

Summary for 7DD3

• Entry DOI: 10.2210/pdb7dd3/pdb
• EMDB information: 30643
• Descriptor: PRP2 isoform 1, Pre-mRNA-splicing factor SPP2, pre-mRNA (3 entities in total)
• Functional Keywords: rna splicing, spliceosome, bact complex, prp2, spp2, deah-box atpase/helicase, splicing
• Biological source: Saccharomyces cerevisiae (Baker's yeast); More
• Total number of polymer chains: 3
• Total formula weight: 123343.40

Authors

Bai, R.,Wan, R.,Yan, C.,Qi, J.,Zhang, P.,Lei, J.,Shi, Y. (deposition date: 2020-10-27, release date: 2021-01-06, Last modification date: 2024-03-27)

• Primary citation: Bai, R.,Wan, R.,Yan, C.,Jia, Q.,Lei, J.,Shi, Y.; Mechanism of spliceosome remodeling by the ATPase/helicase Prp2 and its coactivator Spp2.; Science, 371:-, 2021; PubMed: 33243853; DOI: 10.1126/science.abe8863

Experimental method

ELECTRON MICROSCOPY (3.2 Å)