Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

8R57
DownloadVisualize
BU of 8r57 by Molmil
CryoEM structure of wheat 40S ribosomal subunit, head domain
Descriptor: 40S ribosomal protein S12, 40S ribosomal protein S15, 40S ribosomal protein S16, ...
Authors:Kravchenko, O.V, Baymukhametov, T.N, Afonina, Z.A, Vasilenko, K.S.
Deposit date:2023-11-16
Release date:2023-12-27
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (2.55 Å)
Cite:High-Resolution Structure and Internal Mobility of a Plant 40S Ribosomal Subunit.
Int J Mol Sci, 24, 2023
8R5H
DownloadVisualize
BU of 8r5h by Molmil
Ubiquitin ligation to neosubstrate by a cullin-RING E3 ligase & Cdc34: NEDD8-CUL2-RBX1-ELOB/C-VHL-MZ1 with trapped UBE2R2~donor UB-BRD4 BD2
Descriptor: (2~{S},4~{R})-1-[(2~{S})-2-[2-[2-[2-[2-[2-[(9~{S})-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.0^{2,6}]trideca-2(6),4,7,10,12-pentaen-9-yl]ethanoylamino]ethoxy]ethoxy]ethoxy]ethanoylamino]-3,3-dimethyl-butanoyl]-~{N}-[[4-(4-methyl-2,3-dihydro-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, 5-azanylpentan-2-one, Bromodomain-containing protein 4, ...
Authors:Liwocha, J, Prabu, J.R, Kleiger, G, Schulman, B.A.
Deposit date:2023-11-16
Release date:2024-02-21
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (3.44 Å)
Cite:Cullin-RING ligases employ geometrically optimized catalytic partners for substrate targeting.
Mol.Cell, 84, 2024
8UZH
DownloadVisualize
BU of 8uzh by Molmil
SUMO fused Trehalose Synthase (TreS) of Mycobacterium tuberculosis
Descriptor: CALCIUM ION, SUMO fused Trehalose Synthase (TreS),Trehalose synthase/amylase TreS
Authors:Pathirage, R, Ronning, D.R.
Deposit date:2023-11-15
Release date:2024-03-27
Last modified:2024-04-24
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Targeting Mycobacterium tuberculosis Persistence through Inhibition of the Trehalose Catalytic Shift.
Acs Infect Dis., 10, 2024
8R1F
DownloadVisualize
BU of 8r1f by Molmil
Monomeric E6AP-E6-p53 ternary complex
Descriptor: Cellular tumor antigen p53, Ubiquitin-like protein SMT3,Protein E6, Ubiquitin-protein ligase E3A, ...
Authors:Sandate, C.R, Chakraborty, D, Kater, L, Kempf, G, Thoma, N.H.
Deposit date:2023-11-01
Release date:2023-12-06
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.67 Å)
Cite:Structural insights into viral hijacking of p53 by E6 and E6AP
Biorxiv, 2023
8R1G
DownloadVisualize
BU of 8r1g by Molmil
Dimeric ternary structure of E6AP-E6-p53
Descriptor: Cellular tumor antigen p53, Ubiquitin-like protein SMT3,Protein E6, Ubiquitin-protein ligase E3A, ...
Authors:Sandate, C.R, Chakrabory, D, Kater, L, Kempf, G, Thoma, N.H.
Deposit date:2023-11-01
Release date:2023-12-06
Last modified:2024-06-19
Method:ELECTRON MICROSCOPY (3.99 Å)
Cite:Structural insights into viral hijacking of p53 by E6 and E6AP
Biorxiv, 2023
8R08
DownloadVisualize
BU of 8r08 by Molmil
Cryo-EM structure of the cross-exon pre-B+AMPPNP complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, NHP2-like protein 1, N-terminally processed, ...
Authors:Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
Deposit date:2023-10-31
Release date:2024-05-22
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (6.1 Å)
Cite:Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
8R09
DownloadVisualize
BU of 8r09 by Molmil
Cryo-EM structure of the cross-exon pre-B+5'ss+ATPgammaS complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, NHP2-like protein 1, ...
Authors:Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
Deposit date:2023-10-31
Release date:2024-05-22
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4.3 Å)
Cite:Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
8R0B
DownloadVisualize
BU of 8r0b by Molmil
Cryo-EM structure of the cross-exon pre-B+ATP complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, NHP2-like protein 1, ...
Authors:Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
Deposit date:2023-10-31
Release date:2024-05-22
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4.4 Å)
Cite:Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
8R0A
DownloadVisualize
BU of 8r0a by Molmil
Cryo-EM structure of the cross-exon pre-B+5'ss complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, NHP2-like protein 1, ...
Authors:Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
Deposit date:2023-10-31
Release date:2024-05-22
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (5.8 Å)
Cite:Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
8QZS
DownloadVisualize
BU of 8qzs by Molmil
Cryo-EM structure of the cross-exon B-like complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, Microfibrillar-associated protein 1, NHP2-like protein 1, ...
Authors:Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
Deposit date:2023-10-29
Release date:2024-05-22
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
8QXD
DownloadVisualize
BU of 8qxd by Molmil
Cryo-EM structure of the cross-exon pre-B complex
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, NHP2-like protein 1, N-terminally processed, ...
Authors:Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
Deposit date:2023-10-24
Release date:2024-05-22
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (9.6 Å)
Cite:Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
8QW7
DownloadVisualize
BU of 8qw7 by Molmil
Crystal Structure of compound 4 in complex with KRAS G12V C118S GDP and pVHL:ElonginC:ElonginB
Descriptor: (2S,4R)-1-[(2R)-2-[3-[4-[(3S)-4-[4-[5-[(4S)-2-azanyl-3-cyano-4-methyl-6,7-dihydro-5H-1-benzothiophen-4-yl]-1,2,4-oxadiazol-3-yl]pyrimidin-2-yl]-3-methyl-1,4-diazepan-1-yl]butoxy]-1,2-oxazol-5-yl]-3-methyl-butanoyl]-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ...
Authors:Zollman, D, Farnaby, W, Ciulli, A.
Deposit date:2023-10-18
Release date:2023-12-06
Method:X-RAY DIFFRACTION (2.36 Å)
Cite:Targeting cancer with small molecule pan-KRAS degraders
Biorxiv, 2023
8QVU
DownloadVisualize
BU of 8qvu by Molmil
Crystal Structure of ligand ACBI3 in complex with KRAS G12D C118S GDP and pVHL:ElonginC:ElonginB complex
Descriptor: (2S,4R)-1-[(2S)-2-[4-[4-[(3S)-4-[4-[5-[(4S)-2-azanyl-3-cyano-4-methyl-6,7-dihydro-5H-1-benzothiophen-4-yl]-1,2,4-oxadiazol-3-yl]pyrimidin-2-yl]-3-methyl-1,4-diazepan-1-yl]butoxy]-1,2,3-triazol-1-yl]-3-methyl-butanoyl]-N-[(1R)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]-2-oxidanyl-ethyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ...
Authors:Wijaya, A.J, Zollman, D, Farnaby, W, Ciulli, A.
Deposit date:2023-10-18
Release date:2023-12-06
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Targeting cancer with small molecule pan-KRAS degraders
Biorxiv, 2023
8QW6
DownloadVisualize
BU of 8qw6 by Molmil
Crystal Structure of compound 3 in complex with KRAS G12V C118S GDP and pVHL:ElonginC:ElonginB
Descriptor: (2S,4R)-1-[(2S)-2-[6-[(3S)-4-[4-[5-[(4S)-2-azanyl-3-cyano-4-methyl-6,7-dihydro-5H-1-benzothiophen-4-yl]-1,2,4-oxadiazol-3-yl]pyrimidin-2-yl]-3-methyl-1,4-diazepan-1-yl]hexanoylamino]-3,3-dimethyl-butanoyl]-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ...
Authors:Zollman, D, Farnaby, W, Ciulli, A.
Deposit date:2023-10-18
Release date:2023-12-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Targeting cancer with small molecule pan-KRAS degraders
Biorxiv, 2023
8QU8
DownloadVisualize
BU of 8qu8 by Molmil
PROTAC-mediated complex of KRAS with VHL/Elongin-B/Elongin-C/Cullin-2/Rbx1
Descriptor: (2S,4R)-1-[(2S)-2-[4-[4-[(3S)-4-[4-[5-[(4S)-2-azanyl-3-cyano-4-methyl-6,7-dihydro-5H-1-benzothiophen-4-yl]-1,2,4-oxadiazol-3-yl]pyrimidin-2-yl]-3-methyl-1,4-diazepan-1-yl]butoxy]-1,2,3-triazol-1-yl]-3-methyl-butanoyl]-N-[(1R)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]-2-oxidanyl-ethyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Cullin-2, E3 ubiquitin-protein ligase RBX1, ...
Authors:Fischer, G, Peter, D, Arce-Solano, S.
Deposit date:2023-10-14
Release date:2023-12-06
Last modified:2024-01-24
Method:ELECTRON MICROSCOPY (3.5 Å)
Cite:Targeting cancer with small molecule pan-KRAS degraders
Biorxiv, 2023
8WQA
DownloadVisualize
BU of 8wqa by Molmil
Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 1)
Descriptor: Coiled-coil domain-containing protein 89, Cullin-2, E3 ubiquitin-protein ligase RBX1, ...
Authors:Chen, X, Zhang, K, Xu, C.
Deposit date:2023-10-11
Release date:2024-04-03
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.39 Å)
Cite:Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
8WQH
DownloadVisualize
BU of 8wqh by Molmil
cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 2)
Descriptor: Coiled-coil domain-containing protein 89, Cullin-2, E3 ubiquitin-protein ligase RBX1, ...
Authors:Chen, X, Zhang, K, Xu, C.
Deposit date:2023-10-11
Release date:2024-04-03
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.44 Å)
Cite:Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
8WQB
DownloadVisualize
BU of 8wqb by Molmil
Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 2)
Descriptor: Coiled-coil domain-containing protein 89, Cullin-2, E3 ubiquitin-protein ligase RBX1, ...
Authors:Chen, X, Zhang, K, Xu, C.
Deposit date:2023-10-11
Release date:2024-04-03
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.37 Å)
Cite:Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
8WQF
DownloadVisualize
BU of 8wqf by Molmil
cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CUX1 (conformation 2)
Descriptor: Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ...
Authors:Chen, X, Zhang, K, Xu, C.
Deposit date:2023-10-11
Release date:2024-04-03
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.27 Å)
Cite:Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
8WQE
DownloadVisualize
BU of 8wqe by Molmil
Cryo-EM structure of CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CUX1 (conformation 1)
Descriptor: Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ...
Authors:Chen, X, Zhang, K, Xu, C.
Deposit date:2023-10-11
Release date:2024-04-03
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
8WQC
DownloadVisualize
BU of 8wqc by Molmil
cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CDK5R1
Descriptor: Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ...
Authors:Chen, X, Zhang, K, Xu, C.
Deposit date:2023-10-11
Release date:2024-04-03
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (3.54 Å)
Cite:Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
8WQG
DownloadVisualize
BU of 8wqg by Molmil
cryo-EM structure of neddylated CUL2-RBX1-ELOB-ELOC-FEM1B bound with the C-degron of CCDC89 (conformation 1)
Descriptor: Cullin-2, E3 ubiquitin-protein ligase RBX1, N-terminally processed, ...
Authors:Chen, X, Zhang, K, Xu, C.
Deposit date:2023-10-11
Release date:2024-04-03
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (4.09 Å)
Cite:Mechanism of Psi-Pro/C-degron recognition by the CRL2 FEM1B ubiquitin ligase.
Nat Commun, 15, 2024
8QPK
DownloadVisualize
BU of 8qpk by Molmil
Cryo-EM Structure of Pre-B+5'ss Complex (core part)
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
Deposit date:2023-10-02
Release date:2024-05-22
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
8QPB
DownloadVisualize
BU of 8qpb by Molmil
Cryo-EM Structure of Pre-B+ATP Complex (core part)
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, 5'ss oligo, INOSITOL HEXAKISPHOSPHATE, ...
Authors:Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
Deposit date:2023-10-01
Release date:2024-05-22
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024
8QPE
DownloadVisualize
BU of 8qpe by Molmil
Cryo-EM Structure of Pre-B-like Complex (core part)
Descriptor: 116 kDa U5 small nuclear ribonucleoprotein component, INOSITOL HEXAKISPHOSPHATE, Microfibrillar-associated protein 1, ...
Authors:Zhang, Z, Kumar, V, Dybkov, O, Will, C.L, Zhong, J, Ludwig, S, Urlaub, H, Kastner, B, Stark, H, Luehrmann, R.
Deposit date:2023-10-01
Release date:2024-05-22
Last modified:2024-07-10
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural insights into the cross-exon to cross-intron spliceosome switch.
Nature, 630, 2024

223532

건을2024-08-07부터공개중

PDB statisticsPDBj update infoContact PDBjnumon