8R1G

Dimeric ternary structure of E6AP-E6-p53

Summary for 8R1G

• Entry DOI: 10.2210/pdb8r1g/pdb
• EMDB information: 18810
• Descriptor: Ubiquitin-protein ligase E3A, Ubiquitin-like protein SMT3,Protein E6, Cellular tumor antigen p53, ... (4 entities in total)
• Functional Keywords: e3 ligase, viral protein, transcription factor, ligase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 363659.73

Authors

Sandate, C.R.,Chakrabory, D.,Kater, L.,Kempf, G.,Thoma, N.H. (deposition date: 2023-11-01, release date: 2023-12-06, Last modification date: 2024-06-19)

• Primary citation: Sandate, C.R.,Chakraborty, D.,Kater, L.,Kempf, G.,Thoma, N.H.; Structural insights into viral hijacking of p53 by E6 and E6AP; Biorxiv, 2023; DOI: 10.1101/2023.11.01.565136

Experimental method

ELECTRON MICROSCOPY (3.99 Å)