8R0A

Cryo-EM structure of the cross-exon pre-B+5'ss complex

This is a non-PDB format compatible entry.

Summary for 8R0A

• Entry DOI: 10.2210/pdb8r0a/pdb
• EMDB information: 18788
• Descriptor: U5 snRNA, pre-mRNA, 5'ss oligo, ... (48 entities in total)
• Functional Keywords: spliceosome, splicing
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 62
• Total formula weight: 2806145.12

Authors

Zhang, Z.,Kumar, V.,Dybkov, O.,Will, C.L.,Zhong, J.,Ludwig, S.,Urlaub, H.,Kastner, B.,Stark, H.,Luehrmann, R. (deposition date: 2023-10-31, release date: 2024-05-22, Last modification date: 2024-06-05)

• Primary citation: Zhang, Z.,Kumar, V.,Dybkov, O.,Will, C.L.,Zhong, J.,Ludwig, S.E.J.,Urlaub, H.,Kastner, B.,Stark, H.,Luhrmann, R.; Structural insights into the cross-exon to cross-intron spliceosome switch.; Nature, 2024; PubMed: 38778104; DOI: 10.1038/s41586-024-07458-1

Experimental method

ELECTRON MICROSCOPY (5.8 Å)